Found 155 with Last Name = 'pors' and Initial = 'k' 
Affinity DataKi: 0.0460nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0585nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0637nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.122nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.127nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.131nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.143nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.183nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.198nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 0.367nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to pig brain tubulinMore data for this Ligand-Target Pair
3D Structure (crystal)TargetAldehyde dehydrogenase, dimeric NADP-preferring(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysisMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, dimeric NADP-preferring(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysisMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as increase in Km without change in Vmax using hexanal as substra...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataKi: <1.00E+3nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as increase in Km without change in Vmax using hexanal as substra...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataKi: <1.00E+3nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as increase in Km without change in Vmax using hexanal as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Bioactivation in CYP1A1 (unknown origin) transfected CHO cells assessed as CYP1A1-mediated drug activation by measuring reduction in cell viabilityMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 assessed as reduction in NADPH-dependent 9,10-phenanthrenequinone convers...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of AKR1C3 (unknown origin) using S-tetralol as substrate in presence of NADP+ by fluorimteryMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Bradford
Curated by ChEMBL
University Of Bradford
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human AKR1C3 transfected in Escherichia coli BL21 (DE) assessed as reduction in NADPH production using S-tetralol as substr...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Turin
Curated by ChEMBL
University Of Turin
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human AKR1C3 expressed in Escherichia coli BL21 (DE) Codon Plus RP cells using S-tetralol as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Bioactivation in CYP1A1 (unknown origin) transfected CHO cells assessed as CYP1A1-mediated drug activation by measuring reduction in cell viabilityMore data for this Ligand-Target Pair
