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Found 31 with Last Name = 'porzel' and Initial = 'a'
TargetCholinesterase(Equus caballus (Horse))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  10nMAssay Description:Inhibition of equine serum BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536193(CHEMBL548646 | GNF-Pf-1447 | TCMDC-125419)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536191(CHEMBL4584780)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536194(CHEMBL4569641)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536191(CHEMBL4584780)
Affinity DataIC50:  700nMAssay Description:Inhibition of human CYP2D6 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 7-methoxy-4-(a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536194(CHEMBL4569641)
Affinity DataIC50:  700nMAssay Description:Inhibition of human CYP2D6 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 7-methoxy-4-(a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  710nMAssay Description:Inhibition of bovine AChE by Elman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Equus caballus (Horse))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of equine serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536191(CHEMBL4584780)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human CYP2C9 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 7-methoxy-4-(t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of bovine AChE by Elman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536194(CHEMBL4569641)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human CYP2C9 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 7-methoxy-4-(t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM50222010((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of equine BChE at 100 uM by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536191(CHEMBL4584780)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human CYP2C19 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 3-Cyano-7-Eth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of bovine AChE by Elman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM50308337(CHEMBL589070 | Infractopicrin)
Affinity DataIC50:  9.72E+3nMAssay Description:Inhibition of bovine AChE by Elman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50550150(CHEMBL4764214)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG by IonWorks patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50550151(CHEMBL4783407)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human ERG by IonWorks patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50550149(CHEMBL4781713)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG by IonWorks patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50550148(CHEMBL4756468)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG by IonWorks patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM50308338(10-Hydroxy-infractopicrin | CHEMBL589071)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of bovine AChE by Elman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50550147(DDD-107498 | DDD107498 | DDD498 | M-5717 | M5717 |...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human ERG by IonWorks patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of equine serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536194(CHEMBL4569641)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human CYP2C19 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 3-Cyano-7-Eth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536192(CHEMBL4570567)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Diethoxyfluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536192(CHEMBL4570567)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human CYP2C19 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 3-Cyano-7-Eth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536192(CHEMBL4570567)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human CYP2D6 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 7-methoxy-4-(a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Institute Of Plant Biochemistry

Curated by ChEMBL
LigandPNGBDBM50222010((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  6.33E+4nMAssay Description:Inhibition of bovine AChE at 100 uM by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536192(CHEMBL4570567)
Affinity DataIC50:  8.20E+4nMAssay Description:Inhibition of human CYP2C9 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using 7-methoxy-4-(t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536191(CHEMBL4584780)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of human CYP1A2 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Ethoxyresorufi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536194(CHEMBL4569641)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Ethoxyresorufi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50536192(CHEMBL4570567)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in Escherichia coli pre-incubated for 5 mins before regenerating cofactor solution addition using Ethoxyresorufi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed