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Found 192 with Last Name = 'poutiainen' and Initial = 'p'
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004836(CHEMBL2324047)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004877(CHEMBL2324088)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004876(CHEMBL2324042)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004875(CHEMBL2324086)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004874(CHEMBL2324045)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004873(CHEMBL2324053)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004872(CHEMBL2324097)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004871(CHEMBL2324068)
Affinity DataIC50:  0.870nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004870(CHEMBL2324051)
Affinity DataIC50:  0.890nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004869(CHEMBL2324082)
Affinity DataIC50:  0.910nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004868(CHEMBL2324044)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004865(CHEMBL2324104)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004866(CHEMBL2324101)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004867(CHEMBL2324092)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004864(CHEMBL2324058)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004862(CHEMBL2324076)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004861(CHEMBL2324056)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004860(CHEMBL2324095)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004859(CHEMBL2324084)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50073104(CHEMBL3410856)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [3H]R1881 from pSG5-tagged human androgen receptor expressed in COS1 cells assessed as relative binding inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50073104(CHEMBL3410856)
Affinity DataIC50:  2.10nMAssay Description:Antagonist activity against pSG5-tagged human androgen receptor expressed in COS1 cells assessed as reduction in receptor-mediated transcriptional ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004858(CHEMBL2324103)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116512(CHEMBL3609741)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116512(CHEMBL3609741)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116512(CHEMBL3609741)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116512(CHEMBL3609741)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116513(CHEMBL3609743)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116513(CHEMBL3609743)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  4.20nMAssay Description:Antagonist activity against pSG5-tagged human androgen receptor expressed in COS1 cells assessed as reduction in receptor-mediated transcriptional ac...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50031313(CHEMBL3357575)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [3H]ML128 from rat mGlu4 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50031313(CHEMBL3357575)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [3H]ML128 from rat mGlu4 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of [3H]R1881 from pSG5-tagged human androgen receptor expressed in COS1 cells assessed as relative binding inhibitionMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
University Of Gothenburg

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  4.57nMAssay Description:Displacement of [3H]R1881 from wild type human androgen receptor expressed in COS-1 cells co-transfected with pSG5 after 15 mins by scintillation ass...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293720(CHEMBL541754 | N-(3-(difluoromethoxy)phenyl)picoli...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293720(CHEMBL541754 | N-(3-(difluoromethoxy)phenyl)picoli...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116520(CHEMBL1300476)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116520(CHEMBL1300476)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293721(CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50293721(CHEMBL562551 | N-(4-chloro-3-methoxyphenyl)picolin...)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50031312(CHEMBL3357574)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [3H]ML128 from rat mGlu4 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50031312(CHEMBL3357574)
Affinity DataIC50:  5.10nMAssay Description:Displacement of [3H]ML128 from rat mGlu4 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
University Of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50004857(CHEMBL2324093)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of recombinant firefly luciferase after 20 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116509(CHEMBL3609738)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116509(CHEMBL3609738)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116472(CHEMBL3609734)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116472(CHEMBL3609734)
Affinity DataIC50:  6.70nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116461(CHEMBL3608323)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116508(CHEMBL3609737)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116461(CHEMBL3608323)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116508(CHEMBL3609737)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [3H]N-(4-chloro-3-methoxyphenyl)picolinamide from human mGlu4 receptor expressed in CHO cell membranes incubated for 30 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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