Affinity DataKi: 1.10nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Partial agonist activity at human CRTH2 receptor expressed in HEK cells assessed as forskolin-induced cAMP formation preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 2.97nM ΔG°: -49.5kJ/mole IC50: 6.99nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 6.66nM ΔG°: -47.5kJ/mole IC50: 15.6nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 7.17nM ΔG°: -47.3kJ/mole IC50: 16.9nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 9.34nM ΔG°: -46.6kJ/mole IC50: 21.9nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 11.1nM ΔG°: -46.2kJ/mole IC50: 26.1nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity to Bcl-xL (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 38.7nM ΔG°: -43.0kJ/mole IC50: 91.0nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins follow...More data for this Ligand-Target Pair
TargetTranslocator protein(Rattus norvegicus (rat))
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Toxicology Academy of Military Medical Sciences P.L.A.
US Patent
Affinity DataKi: 49.2nM ΔG°: -42.4kJ/mole IC50: 116nMT: 2°CAssay Description:Competitive Binding Test of Drug to the Receptor (Rat Heart TSPO) and Radioligand (3H-PK11195): (1) tubes were placed in reaction condition of 30 C.(...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Binding affinity to Bcl-xL (unknown origin)More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.69E+3nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nMAssay Description:Binding affinity to Bcl-xL (unknown origin)More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology
Curated by ChEMBL
Dalian University Of Technology
Curated by ChEMBL
Affinity DataKi: 4.60E+3nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.69E+3nMAssay Description:Binding affinity to Bcl-xL (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.10E+3nMAssay Description:Binding affinity to Bcl-xL (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Lanzhou University
Curated by ChEMBL
Lanzhou University
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Lanzhou University
Curated by ChEMBL
Lanzhou University
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human VEGFR2 after 60 minsMore data for this Ligand-Target Pair