Affinity DataKi: 9.70nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Competitive inhibition of C-terminal His-tagged ZIKV NSB2 (52 to 96 amino acids)-NS3 (1 to 184 amino acids) protease expressed in Escherichia coli BL...More data for this Ligand-Target Pair
Affinity DataKi: 343nMAssay Description:Competitive inhibition of C-terminal His-tagged WNV NSB2 (52 to 96 amino acids)-NS3 (1 to 184 amino acids) protease expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 820nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 850nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of Zika virus NS2B-NS3 protease using Bz-Nle-Lys-Lys-Arg-AMC as substrate preincubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataKi: 3.99E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.23E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.58E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged West Nile virus NS2B (52 to 96 residues)-G4SG4-NS3 (1 to 184 residues) expressed in Escherichia coli BL21(DE3) c...More data for this Ligand-Target Pair
Affinity DataKi: 1.13E+4nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+4nMAssay Description:Inhibition of Zika virus NS2B-NS3 protease using Bz-Nle-Lys-Lys-Arg-AMC as substrate preincubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Affinity DataKi: 1.27E+4nMAssay Description:Competitive inhibition of recombinant N-terminal His-tagged DENV NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using Boc-GRR-AMC as subst...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 1.29E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 1.73E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs...More data for this Ligand-Target Pair
Affinity DataKi: 2.55E+4nMAssay Description:Inhibition of C-terminal His6-tagged West Nile virus NS2B (52 to 96 residues)-G4SG4-NS3 (1 to 184 residues) expressed in Escherichia coli BL21(DE3) c...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin
Curated by ChEMBL
Freie Universit£T Berlin
Curated by ChEMBL
Affinity DataKi: 4.88E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs...More data for this Ligand-Target Pair
Affinity DataKi: 1.97E+5nMAssay Description:Reversible inhibition of Coxsackievirus B3 C-terminal His6-tagged protease 3C expressed in Escherichia coli BL21(DE3) using N-Dabcyl-KTLEALFQGPPVYE-(...More data for this Ligand-Target Pair
Affinity DataKi: 2.72E+5nMAssay Description:Reversible inhibition of Coxsackievirus B3 C-terminal His6-tagged protease 3C expressed in Escherichia coli BL21(DE3) using N-Dabcyl-KTLEALFQGPPVYE-(...More data for this Ligand-Target Pair
Affinity DataKi: 3.93E+5nMAssay Description:Inhibition of Coxsackievirus B3 C-terminal His6-tagged protease 3C expressed in Escherichia coli BL21(DE3) using N-Dabcyl-KTLEALFQGPPVYE-(Edans)-NH2 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair