Compile Data Set for Download or QSAR
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Found 147 with Last Name = 'rademann' and Initial = 'j'
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380548(CHEMBL2019055)
Affinity DataKi:  9.70nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(Zika virus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50587014(CHEMBL5094815)
Affinity DataKi:  79nMAssay Description:Competitive inhibition of C-terminal His-tagged ZIKV NSB2 (52 to 96 amino acids)-NS3 (1 to 184 amino acids) protease expressed in Escherichia coli BL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50587014(CHEMBL5094815)
Affinity DataKi:  343nMAssay Description:Competitive inhibition of C-terminal His-tagged WNV NSB2 (52 to 96 amino acids)-NS3 (1 to 184 amino acids) protease expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50087869(CHEMBL3426914)
Affinity DataKi:  390nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50087871(CHEMBL3426915)
Affinity DataKi:  410nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380542(CHEMBL2019037)
Affinity DataKi:  620nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380544(CHEMBL2019043)
Affinity DataKi:  820nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380545(CHEMBL2019046)
Affinity DataKi:  850nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380543(CHEMBL2019040)
Affinity DataKi:  880nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380546(CHEMBL2019047)
Affinity DataKi:  1.06E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(Zika virus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50538477(CHEMBL4633138)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Zika virus NS2B-NS3 protease using Bz-Nle-Lys-Lys-Arg-AMC as substrate preincubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataKi:  3.99E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380552(CHEMBL2019035)
Affinity DataKi:  4.23E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataKi:  6.58E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50538478(CHEMBL4634219)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of C-terminal His6-tagged West Nile virus NS2B (52 to 96 residues)-G4SG4-NS3 (1 to 184 residues) expressed in Escherichia coli BL21(DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataKi:  1.13E+4nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 3(Zika virus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50538478(CHEMBL4634219)
Affinity DataKi:  1.15E+4nMAssay Description:Inhibition of Zika virus NS2B-NS3 protease using Bz-Nle-Lys-Lys-Arg-AMC as substrate preincubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50587014(CHEMBL5094815)
Affinity DataKi:  1.27E+4nMAssay Description:Competitive inhibition of recombinant N-terminal His-tagged DENV NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using Boc-GRR-AMC as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50087869(CHEMBL3426914)
Affinity DataKi:  1.29E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50087869(CHEMBL3426914)
Affinity DataKi:  1.73E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(West Nile virus)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50538477(CHEMBL4633138)
Affinity DataKi:  2.55E+4nMAssay Description:Inhibition of C-terminal His6-tagged West Nile virus NS2B (52 to 96 residues)-G4SG4-NS3 (1 to 184 residues) expressed in Escherichia coli BL21(DE3) c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50087869(CHEMBL3426914)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50087871(CHEMBL3426915)
Affinity DataKi:  4.88E+4nMAssay Description:Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50501750(CHEMBL4096676)
Affinity DataKi:  1.97E+5nMAssay Description:Reversible inhibition of Coxsackievirus B3 C-terminal His6-tagged protease 3C expressed in Escherichia coli BL21(DE3) using N-Dabcyl-KTLEALFQGPPVYE-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50501751(CHEMBL4096233)
Affinity DataKi:  2.72E+5nMAssay Description:Reversible inhibition of Coxsackievirus B3 C-terminal His6-tagged protease 3C expressed in Escherichia coli BL21(DE3) using N-Dabcyl-KTLEALFQGPPVYE-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50501749(CHEMBL4068292)
Affinity DataKi:  3.93E+5nMAssay Description:Inhibition of Coxsackievirus B3 C-terminal His6-tagged protease 3C expressed in Escherichia coli BL21(DE3) using N-Dabcyl-KTLEALFQGPPVYE-(Edans)-NH2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380559(CHEMBL2019048)
Affinity DataIC50:  0.0350nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380553(CHEMBL2019034)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380558(CHEMBL2019049)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380547(CHEMBL2019053)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380552(CHEMBL2019035)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380551(CHEMBL2019038)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380552(CHEMBL2019035)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380542(CHEMBL2019037)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380537(CHEMBL2019030)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380559(CHEMBL2019048)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380537(CHEMBL2019030)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380550(CHEMBL2019041)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380536(CHEMBL2019031)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380553(CHEMBL2019034)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380542(CHEMBL2019037)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380546(CHEMBL2019047)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380551(CHEMBL2019038)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380552(CHEMBL2019035)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380539(CHEMBL2019028)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380543(CHEMBL2019040)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380538(CHEMBL2019029)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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