Affinity DataKi: 2.60E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 8.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 1.26E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 1.61E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 1.64E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 1.78E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 2.24E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 2.26E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 2.77E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 3.01E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 9.41E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 3.03E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Affinity DataKi: 3.41E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EGFR tyrosine kinase expressed in A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of EGFR tyrosine kinase expressed in A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
Affinity DataIC50: 40nMpH: 7.7Assay Description:Total volume of the reaction mixture was 100 µL containing 60 µL, Na2HPO4 buffer, 50 mM and pH 7.7. Ten µL test compound 0.5 mM well-1 was added foll...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Mcgill University/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of EGFR tyrosine kinase expressed in A431 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Mcgill University Health Center/Royal Victoria Hospital
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Imam Abdulrahman Bin Faisal University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair