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Found 707 with Last Name = 'rahim' and Initial = 'f'
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222139(Chymostatin | US11859014, Compound chymostatin)
Affinity DataKi:  2.60E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50289012(2-(2-Fluoro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-...)
Affinity DataKi:  4.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50077011(2-Phenyl-4H-3,1-benzoxazin-4-one (3) | 2-Phenyl-be...)
Affinity DataKi:  8.70E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222117(2-(2-Thienyl)-4H-3,1-benzoxazin-4-one (4) | US1158...)
Affinity DataKi:  9.10E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50289006(2-(2-Bromo-phenyl)-benzo[d][1,3]oxazin-4-one | 2-(...)
Affinity DataKi:  9.10E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222124(2-(2-Methylphenyl)-4H-3,1-benzoxazin-4-one (13))
Affinity DataKi:  9.80E+3nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50289000(2-(2-Methoxy-phenyl)-benzo[d][1,3]oxazin-4-one | 2...)
Affinity DataKi:  1.25E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222118(2-(4-Methoxyphenyl)-4H-3,1-benzoxazin-4-one (5))
Affinity DataKi:  1.26E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222121(2-(3-Methylphenyl)-4H-3,1-benzoxazin-4-one (10))
Affinity DataKi:  1.61E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222119(2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7))
Affinity DataKi:  1.64E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222123(2-(3-Fluorophenyl)-4H-3,1-benzoxazin-4-one (12))
Affinity DataKi:  1.78E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM33703(2-(2-Nitro-phenyl)-benzo[d][1,3]oxazin-4-one | 2-(...)
Affinity DataKi:  2.24E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222125(2-(3-Chlorophenyl)-4H-3,1-benzoxazin-4-one (14))
Affinity DataKi:  2.26E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222122(2-(2,6-Dimethoxyphenyl)-4H-3,1-benzoxazin-4-one (1...)
Affinity DataKi:  2.77E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222120(2-(2,6-Difluorophenyl)-4H-3,1-benzoxazin-4-one (8))
Affinity DataKi:  3.01E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222127(2-(4-Fluorophenyl)-4H-3,1-benzoxazin-4-one (16))
Affinity DataKi:  9.41E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222126(2-(3-Methylphenyl)-7-nitro-4H-3,1-benzoxazin-4-one...)
Affinity DataKi:  1.62E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM222128(7-Chloro-2-(2-fluorophenyl)-4H-3,1-benzoxazin-4-on...)
Affinity DataKi:  3.03E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University of Karachi

LigandPNGBDBM50449429(2-(3-Nitrophenyl)-4H-3,1-benzoxazin-4-one (18) | C...)
Affinity DataKi:  3.41E+5nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188463(4-[(3-chlorophenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50:  4nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50211733(1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of EGFR tyrosine kinase expressed in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3535(4-N-(3-bromophenyl)-6-N-methylquinazoline-4,6-diam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50160900(CHEMBL181617 | N*4*-(3-Bromo-phenyl)-N*6*-(2-chlor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188464(4-[(3-methylphenyl)amino]-6-(methylamino)quinazoli...)
Affinity DataIC50:  11nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133385(CHEMBL134312 | N-(3-bromophenyl)-6-[(1E)-3,3-dimet...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133370(CHEMBL136491 | N-(3-chlorophenyl)-6-[(1E)-3,3-dime...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188456(1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quina...)
Affinity DataIC50:  18nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188461(1-(2-chloroethyl)-3-{[4-(3-chlorophenyl)amino]quin...)
Affinity DataIC50:  22nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133379(6-[(1E)-3,3-dimethyltriaz-1-enyl]-N-(3-methylpheny...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133383(6-[(1E)-3-benzyltriaz-1-enyl]-N-(3-bromophenyl)qui...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50160901(CHEMBL179451 | N*6*-(2-Chloro-ethyl)-N*4*-(3-chlor...)
Affinity DataIC50:  26nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50211735(1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-(2-N...)
Affinity DataIC50:  37nMAssay Description:Inhibition of EGFR tyrosine kinase expressed in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133380(CHEMBL137534 | N-(3-bromophenyl)-6-{(1E)-3-[2-(dim...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133373(CHEMBL137617 | N-(3-bromophenyl)-6-[(1E)-3-methylt...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Hazara University

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  40nMpH: 7.7Assay Description:Total volume of the reaction mixture was 100 µL containing 60 µL, Na2HPO4 buffer, 50 mM and pH 7.7. Ten µL test compound 0.5 mM well-1 was added foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Mcgill University/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Abl tyrosine kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(4-Anilinoquinazoline deriv. 45 | 4-N-(3-bromopheny...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(4-Anilinoquinazoline deriv. 45 | 4-N-(3-bromopheny...)
Affinity DataIC50:  44nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM3294(4-Anilinoquinazoline deriv. 45 | 4-N-(3-bromopheny...)
Affinity DataIC50:  44nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188468(1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)a...)
Affinity DataIC50:  47nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133376(6-[(1E)-3-[(2-morpholin-4-yl)-ethyl]triaz-1-enyl]-...)
Affinity DataIC50:  64nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188466(1-(2-Chloroethyl)-1-nitroso-3-{[4-(3-chlorophenyl)...)
Affinity DataIC50:  67nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133374(CHEMBL136674 | N-(3-bromophenyl)-6-[(1E)-3-(2-meth...)
Affinity DataIC50:  71nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50211736(1-{4-[(3-chlorophenyl)amino-6-quinazolinyl}-3-{2-[...)
Affinity DataIC50:  71nMAssay Description:Inhibition of EGFR tyrosine kinase expressed in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50188459(3-(2-chloroethyl)-1-methyl-1-{[4-(3-chlorophenyl)a...)
Affinity DataIC50:  81nMAssay Description:Inhibition of EGFR tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mcgill University Health Center/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50133372(CHEMBL133024 | N-(3-chlorophenyl)-6-[(1E)-3-methyl...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50284071(CHEMBL4165927)
Affinity DataIC50:  100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50284029(CHEMBL4168635)
Affinity DataIC50:  100nMAssay Description:Inhibition of human beta-glucuronidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50:  100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM193733(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...)
Affinity DataIC50:  120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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