Affinity DataKi: 0.320nMAssay Description:Negative logarithm causing 50% receptor occupancy against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Negative logarithm causing 50% receptor occupancy against beta-2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Negative logarithm causing 50% receptor occupancy against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory concentration against angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory concentration against angiotensin II receptor, type 1More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition constant against alpha adrenergic receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition constant against angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Negative logarithm causing 50% receptor occupancy against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibitory concentration against endothelin receptor type AMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity towards KDM4A (unknown origin)More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition constant against dopamine receptor D2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 5.01nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Negative logarithm causing 50% receptor occupancy against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Inhibition constant against nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity towards KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibitory concentration against endothelin receptor type AMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory concentration against endothelin receptor type AMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory concentration against angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: >10nMAssay Description:Inhibitory concentration against angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition constant against endothelin converting enzyme 1More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition constant against serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition constant against thromboxane A2 receptor to prostaglandin H2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition constant against histamine H3 receptorMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition constant against norepinephrine transporterMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition constant against alpha adrenergic receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]naloxone from MOR (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibitory concentration against neutral endopeptidaseMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Negative logarithm causing 50% receptor occupancy against tachykinin receptor 1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assayMore data for this Ligand-Target Pair