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Found 77 with Last Name = 'romero' and Initial = 't'
LigandPNGBDBM50615191(CHEMBL5271804)
Affinity DataIC50:  30nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of [33P]gamma-ATP and ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50615191(CHEMBL5271804)
Affinity DataIC50:  40nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of [33P]gamma-ATP and ATP by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
LigandPNGBDBM6309(6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-y...)
Affinity DataIC50:  208nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584985(CHEMBL5083265)
Affinity DataIC50:  631nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584991(CHEMBL5077987)
Affinity DataIC50:  631nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584990(CHEMBL5077419)
Affinity DataIC50:  794nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50:  794nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
LigandPNGBDBM50511422(CHEMBL4446338)
Affinity DataIC50:  950nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50585011(CHEMBL5094080)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50615192(CHEMBL4284012)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of PI5P4Kalpha in human HeLa cells pre-incubated for 1 hr followed by ATP addition measured after 90 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584993(CHEMBL5092753)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM60983((E)-2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50497347(CHEMBL1529478)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-fused human recombinant PI5P4Kgamma expressed in Escherichia coli BL21 (DE3) using dipalmitoyl-PI5P and [gamma-32P]ATP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human full length PI5P4Kbeta expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584989(CHEMBL5084764)
Affinity DataIC50:  3.16E+3nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584987(CHEMBL5076920)
Affinity DataIC50:  3.98E+3nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50511426(CHEMBL1378392)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of GST-fused human recombinant PI5P4Kgamma expressed in Escherichia coli BL21 (DE3) using dipalmitoyl-PI5P and [gamma-32P]ATP as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human full length PI5P4Kalpha expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50584987(CHEMBL5076920)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50497347(CHEMBL1529478)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50033288((2-Phenyl-quinazolin-4-yl)-thiophen-2-ylmethyl-ami...)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50584981(CHEMBL1394113)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50584982(CHEMBL1479741)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584983(CHEMBL5083347)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497353(CHEMBL3356099)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584984(CHEMBL5079093)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584985(CHEMBL5083265)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584986(CHEMBL5069855)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584987(CHEMBL5076920)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584988(CHEMBL5090399)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584989(CHEMBL5084764)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584990(CHEMBL5077419)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584991(CHEMBL5077987)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50584993(CHEMBL5092753)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584982(CHEMBL1479741)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497347(CHEMBL1529478)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50584994(CHEMBL5074668)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584983(CHEMBL5083347)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497353(CHEMBL3356099)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584995(CHEMBL1317494)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584996(CHEMBL5086996)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584984(CHEMBL5079093)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584997(CHEMBL5089416)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584998(CHEMBL5078734)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50584999(CHEMBL5091771)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50585000(CHEMBL5087252)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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