TargetN-acetyltransferase Eis(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis Eis assessed as reduction in Eis-mediated kanamycin acetylation preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetN-acetyltransferase Eis(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis Eis assessed as reduction in Eis-mediated kanamycin acetylation preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetN-acetyltransferase Eis(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Kentucky
Curated by ChEMBL
University Of Kentucky
Curated by ChEMBL
Affinity DataKi: 910nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis Eis assessed as reduction in Eis-mediated kanamycin acetylation preincubated for 10 mins followe...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of [3H]ifenprodil from human NR1-1a/NR2B receptor expressed in mouse L13-E6 cellsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 0.492nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.507nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of LysoPLD activity of ATX in human plasma assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human ATX assessed as reduction in choline release using LPC(16:0) as substrate incubated for 15 hrsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 113nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Friedrich-Schiller-Universitat Jena
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Inhibition of electric eel AChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of equine serum BChE by modified Ellman's methodMore data for this Ligand-Target Pair