TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of LPS-stimulated p38-related TNF-alpha production in human peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of LPS-stimulated p38-related IL1-beta production in human peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of LPS-stimulated p38-related TNF-alpha production in human peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of LPS-stimulated p38-related TNF-alpha production in human peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of LPS-stimulated p38-related IL1-beta production in human peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of LPS-stimulated p38-related IL1-beta production in human peripheral blood mononuclear cells (PBMC)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Inhibitory activity against LPS-stimulated TNF-alpha production in human monocytic cells (THP-1)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 142nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 142nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair