Affinity DataKi: 1.14E+3nM ΔG°: -31.2kJ/mole IC50: 5.90E+3nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 3.43E+3nM ΔG°: -28.7kJ/mole IC50: 3.58E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 3.88E+3nM ΔG°: -28.4kJ/mole IC50: 3.43E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 7.91E+3nM ΔG°: -26.8kJ/mole IC50: 2.08E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 1.38E+4nM ΔG°: -25.5kJ/mole IC50: 4.41E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 1.41E+4nM ΔG°: -25.5kJ/mole IC50: 4.02E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 1.72E+4nM ΔG°: -25.0kJ/mole IC50: 5.86E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 2.72E+4nM ΔG°: -24.0kJ/mole IC50: 9.11E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 3.19E+4nM ΔG°: -23.6kJ/mole IC50: 9.31E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Affinity DataKi: 3.32E+4nM ΔG°: -23.5kJ/mole IC50: 1.14E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad
Curated by ChEMBL
Ferdowsi University Of Mashhad
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad
Curated by ChEMBL
Ferdowsi University Of Mashhad
Curated by ChEMBL
Affinity DataIC50: 1.56E+3nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 2.84E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad
Curated by ChEMBL
Ferdowsi University Of Mashhad
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad
Curated by ChEMBL
Ferdowsi University Of Mashhad
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 5.67E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University
Curated by ChEMBL
Islamic Azad University
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad
Curated by ChEMBL
Ferdowsi University Of Mashhad
Curated by ChEMBL
Affinity DataIC50: 1.92E+4nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences
Curated by ChEMBL
Mashhad University Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair