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Found 69 with Last Name = 'sadeghian' and Initial = 'h'
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234360(2-Allyl-1-isopropoxy-4-methoxybenzene (4d))
Affinity DataKi:  1.14E+3nM ΔG°:  -31.2kJ/mole IC50:  5.90E+3nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234363(2-Allyl-1-isobutoxy-4-methoxybenzene (4g))
Affinity DataKi:  3.43E+3nM ΔG°:  -28.7kJ/mole IC50:  3.58E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234359(2-Allyl-4-methoxy-1-propoxybenzene (4c))
Affinity DataKi:  3.88E+3nM ΔG°:  -28.4kJ/mole IC50:  3.43E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234362(2-Allyl-1-sec-butoxy-4-methoxybenzene (4f))
Affinity DataKi:  7.91E+3nM ΔG°:  -26.8kJ/mole IC50:  2.08E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234366(2-Allyl-1-cyclohexyloxy-4-methoxybenzene (4j))
Affinity DataKi:  1.38E+4nM ΔG°:  -25.5kJ/mole IC50:  4.41E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234365(2-Allyl-1-cyclopentyloxy-4-methoxybenzene (4i))
Affinity DataKi:  1.41E+4nM ΔG°:  -25.5kJ/mole IC50:  4.02E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234361(2-Allyl-1-butoxy-4-methoxybenzene (4e))
Affinity DataKi:  1.72E+4nM ΔG°:  -25.0kJ/mole IC50:  5.86E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234358(2-Allyl-1-ethoxy-4-methoxybenzene (4b))
Affinity DataKi:  2.72E+4nM ΔG°:  -24.0kJ/mole IC50:  9.11E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234357(2-Allyl-1,4-dimethoxybenzene (4a))
Affinity DataKi:  3.19E+4nM ΔG°:  -23.6kJ/mole IC50:  9.31E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 9S-lipoxygenase-3(Glycine max (Soybean))
Mashhad University of Medical Sciences

LigandPNGBDBM234364(2-Allyl-1- tert-butoxy-4-methoxybenzene (4h))
Affinity DataKi:  3.32E+4nM ΔG°:  -23.5kJ/mole IC50:  1.14E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308952(4-Methyl-6-({3-[(4-methylpiperidino)carbonyl]-benz...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Ferdowsi University of Mashhad

LigandPNGBDBM192765(1,3-Dimethoxy-5-methyl-2-((2E,6E)-3,7,11-trimethyl...)
Affinity DataIC50:  520nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308954(4-Methyl-6-{[3-(tetrahydro-1H-1-pyrrolylcarbonyl)-...)
Affinity DataIC50:  640nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308951(4-Methyl-6-{[3-(piperidinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad

Curated by ChEMBL
LigandPNGBDBM50552490(CHEMBL4759600)
Affinity DataIC50:  710nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308949(1-(3-{[(4-Methyl-2-oxo-1,2-dihydro-6-quinolinyl)ox...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308950(6-({3-[(4-Hydroxypiperidino)carbonyl]benzyl}oxy)-4...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308948(4-Methyl-6-(3-[(4-oxopiperidino)carbonyl]benzyloxy...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308954(4-Methyl-6-{[3-(tetrahydro-1H-1-pyrrolylcarbonyl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308948(4-Methyl-6-(3-[(4-oxopiperidino)carbonyl]benzyloxy...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308949(1-(3-{[(4-Methyl-2-oxo-1,2-dihydro-6-quinolinyl)ox...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50391177(CHEMBL2088235)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308953(4-Methyl-6-{[3-(morpholinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308950(6-({3-[(4-Hydroxypiperidino)carbonyl]benzyl}oxy)-4...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308946(4-Methyl-6-({3-[(4-ethylpiperazino)carbonyl]-benzy...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308953(4-Methyl-6-{[3-(morpholinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad

Curated by ChEMBL
LigandPNGBDBM50552491(CHEMBL4777505)
Affinity DataIC50:  1.56E+3nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308952(4-Methyl-6-({3-[(4-methylpiperidino)carbonyl]-benz...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308947(6-[(3-{[4-(2-Hydroxyethyl)piperazino]carbonyl}-ben...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308951(4-Methyl-6-{[3-(piperidinocarbonyl)benzyl]oxy}-1,2...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308945(4-Methyl-6-({3-[(4-methylpiperazino)carbonyl]-benz...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308946(4-Methyl-6-({3-[(4-ethylpiperazino)carbonyl]-benzy...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308947(6-[(3-{[4-(2-Hydroxyethyl)piperazino]carbonyl}-ben...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308956(6-(3-(4-methylpiperazine-1-carbonyl)benzyloxy)quin...)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308945(4-Methyl-6-({3-[(4-methylpiperazino)carbonyl]-benz...)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50391176(CHEMBL2088234)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad

Curated by ChEMBL
LigandPNGBDBM50552489(CHEMBL4763905)
Affinity DataIC50:  4.40E+3nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Ferdowsi University of Mashhad

LigandPNGBDBM192764((E)-2-(3,7-Dimethylocta-2,6-dien-1-yl)-1,3-dimetho...)
Affinity DataIC50:  5.30E+3nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad

Curated by ChEMBL
LigandPNGBDBM50552492(CHEMBL4791550)
Affinity DataIC50:  5.60E+3nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50308956(6-(3-(4-methylpiperazine-1-carbonyl)benzyloxy)quin...)
Affinity DataIC50:  5.67E+3nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50391172(CHEMBL2088232)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Ferdowsi University of Mashhad

LigandPNGBDBM192763(1,3-Dimethoxy-5-methyl-2-(3-methylbut-2-en-1-yl)be...)
Affinity DataIC50:  7.60E+3nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50016980(6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of human PDE3A by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50391171(CHEMBL2088231)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Islamic Azad University

Curated by ChEMBL
LigandPNGBDBM50016980(6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human PDE3B by fluorescence microplate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50391178(CHEMBL2088236)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50143435(7-((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylo...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Ferdowsi University Of Mashhad

Curated by ChEMBL
LigandPNGBDBM50552495(CHEMBL4798338)
Affinity DataIC50:  1.92E+4nMAssay Description:Antagonist activity at human PDL1 assessed as inhibition of human PD1 interaction with human PDL1 by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
Ferdowsi University of Mashhad

LigandPNGBDBM192766(4-MMPB)
Affinity DataIC50:  2.26E+4nMpH: 7.0 T: 2°CAssay Description:Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Mashhad University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50361373(AURAPTENE)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of recombinant human 15-lipoxygenase by MBTH-DMAB methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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