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Found 326 with Last Name = 'saeb' and Initial = 'w'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304196(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304196(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM15344(2-({2,3,5,6-tetrafluoro-4-[3-(trifluoromethoxy)phe...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM16112(2-{[2,3,5,6-tetrafluoro-4-(2-methoxyphenyl)phenyl]...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  9nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304220(CHEMBL593911 | N-[4-(Benzo[d]thiazol-2''-yl)-3-met...)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  16nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50137303(2-(3'-Ethoxy-3,5-difluoro-biphenyl-4-ylcarbamoyl)-...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50137312(2-(2'-Chloro-3,5-difluoro-biphenyl-4-ylcarbamoyl)-...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50137311(2-(2-Chloro-3'-trifluoromethoxy-biphenyl-4-ylcarba...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304200(CHEMBL596292 | N-[4-(6''-Chlorobenzo[d]thiazol-2''...)
Affinity DataIC50:  24nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304199(CHEMBL604992 | N-[4-(6''-Methoxybenzo[d]thiazol-2'...)
Affinity DataIC50:  26nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  26nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  27nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304211(CHEMBL596087 | N-[4-(Benzo[d]thiazol-2''-yl)-2-flu...)
Affinity DataIC50:  32nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304211(CHEMBL596087 | N-[4-(Benzo[d]thiazol-2''-yl)-2-flu...)
Affinity DataIC50:  32nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM15343(2-({2,6-difluoro-4-[3-(trifluoromethoxy)phenyl]phe...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  37nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304208(CHEMBL595406 | N-(4-(benzo[d]thiazol-2-yl)-2-methy...)
Affinity DataIC50:  38nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304198(CHEMBL593274 | N-(4-(benzo[d]thiazol-2-yl)-3-chlor...)
Affinity DataIC50:  38nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304199(CHEMBL604992 | N-[4-(6''-Methoxybenzo[d]thiazol-2'...)
Affinity DataIC50:  41nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50137300(2-(3,5-Difluoro-2'-methoxy-biphenyl-4-ylcarbamoyl)...)
Affinity DataIC50:  42nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304222(CHEMBL604893 | N-[4-(Benzo[d]thiazol-2''-yl)-3-chl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304197(CHEMBL593987 | N-(4-(benzo[d]thiazol-2-yl)-3-fluor...)
Affinity DataIC50:  44nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304203(2-(4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propo...)
Affinity DataIC50:  44nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50137306(2-(3,5,2'-Trifluoro-biphenyl-4-ylcarbamoyl)-cyclop...)
Affinity DataIC50:  45nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304220(CHEMBL593911 | N-[4-(Benzo[d]thiazol-2''-yl)-3-met...)
Affinity DataIC50:  47nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304212(CHEMBL593306 | N-[4-(Benzo[d]thiazol-2''-yl)-3-chl...)
Affinity DataIC50:  48nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50137308(2-(2-Chloro-4'-dimethylamino-biphenyl-4-ylcarbamoy...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304213(CHEMBL593275 | N-[4-(6''-Fluorobenzo[d]thiazol-2''...)
Affinity DataIC50:  54nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304195(CHEMBL606466 | N-[4-(Benzo[d]thiazol-2''-yl)-3-met...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304201(CHEMBL593908 | N-[4-(5''-Chlorobenzo[d]thiazol-2''...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304212(CHEMBL593306 | N-[4-(Benzo[d]thiazol-2''-yl)-3-chl...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304200(CHEMBL596292 | N-[4-(6''-Chlorobenzo[d]thiazol-2''...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)
Affinity DataIC50:  62nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304203(2-(4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propo...)
Affinity DataIC50:  63nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304206(CHEMBL596059 | N-(4-(benzo[d]thiazol-2-yl)-2-metho...)
Affinity DataIC50:  63nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304213(CHEMBL593275 | N-[4-(6''-Fluorobenzo[d]thiazol-2''...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304193(CHEMBL593221 | N-[4-(Benzo[d]thiazol-2''-yl)-2-hyd...)
Affinity DataIC50:  65nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304211(CHEMBL596087 | N-[4-(Benzo[d]thiazol-2''-yl)-2-flu...)
Affinity DataIC50:  68nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(CHEMBL595615 | N-(4-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  69nMAssay Description:Inhibition of VEGFR3 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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