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Found 25 with Last Name = 'sakamaki' and Initial = 'y'
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388528(CHEMBL2058272)
Affinity DataIC50:  0.0290nMAssay Description:Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [3H]-1alpha,25-dihydroxyvitamin D3 from recombinant human VDR LBD expressed in Escherichia coli BL21 (DE3) pLysS after 16 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50129805(CHEMBL3629552)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [3H]-1alpha,25-dihydroxyvitamin D3 from recombinant human VDR LBD expressed in Escherichia coli BL21 (DE3) pLysS after 16 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388529(CHEMBL2058273)
Affinity DataIC50:  0.380nMAssay Description:Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50388530(CHEMBL2058274)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM159600(US8772490, Example 23 | US9035062, 23)
Affinity DataIC50:  650nMpH: 7.0 T: 2°CAssay Description:For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM212440(US8772490, H)
Affinity DataIC50:  650nMpH: 7.0 T: 2°CAssay Description:For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Escherichia coli)
Meiji Seika Pharma

US Patent
LigandPNGBDBM159600(US8772490, Example 23 | US9035062, 23)
Affinity DataIC50:  650nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM191563(US9676777, example 23)
Affinity DataIC50:  650nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM212441(US8772490, TAZ)
Affinity DataIC50:  950nMpH: 7.0 T: 2°CAssay Description:For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  950nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Escherichia coli)
Meiji Seika Pharma

US Patent
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)
Affinity DataIC50:  950nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM191564(US9676777, example 24)
Affinity DataIC50: >3.00E+4nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-lactamase(Escherichia coli)
Meiji Seika Pharma

US Patent
LigandPNGBDBM159601(US8772490, Example 24 | US9035062, 24)
Affinity DataIC50: >3.00E+4nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM159601(US8772490, Example 24 | US9035062, 24)
Affinity DataIC50: >3.00E+4nMpH: 7.0 T: 2°CAssay Description:For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
Meiji Seika Pharma

US Patent
LigandPNGBDBM159601(US8772490, Example 24 | US9035062, 24)
Affinity DataIC50: >3.00E+4nMpH: 7.0 T: 2°CAssay Description:For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293099((1alpha,22S,24S)-22-Butyl-1,24-dihydroxyvitamin D3...)
Affinity DataEC50:  3.80nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293098((1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,2S,4R)-2...)
Affinity DataEC50:  20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293097((1alpha,22R,24S)-22-Butyl-1,24-dihydroxyvitamin D3...)
Affinity DataEC50:  3.40nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293096((1alpha,22R,24R)-22-Butyl-1,24-dihydroxyvitamin D3...)
Affinity DataEC50:  16nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293095(20S,22R-Butyl-1alpha,24-dihydroxy-24,25,26-trinorv...)
Affinity DataEC50:  20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293094((1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2S,3S)-3-(2...)
Affinity DataEC50:  2nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293093((1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,3S)-3-(2...)
Affinity DataEC50:  1.20nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50293092(22R-Butyl-1alpha,24-dihydroxy-24,25,26-trinorvitam...)
Affinity DataEC50:  11nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Bos taurus)
Showa Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  0.0500nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed