Affinity DataKi: 0.140nMAssay Description:Inhibition of human recombinant melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]4-DAMP from human recombinant Muscarinic acetylcholine receptor M3 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]methyl-spiperone from human recombinant D2S receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]U 69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I](+/-)DOI from human recombinant 5-HT2B receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]NKA from human recombinant tachykinin NK2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]nisoxetine from human recombinant norepinephrine transporter expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]BTCP from human recombinant dopamine transporter expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]pirenzepine from human recombinant Muscarinic acetylcholine receptor M1 expressed in CHO cells after 60 mins by scintillation cou...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275RMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220VMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D220VMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human recombinant melanocortin 4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Displacement of [3H]4-DAMP from human recombinant Muscarinic acetylcholine receptor M3 expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in E275RMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration against Protein phosphatase 1 was determined; 0.5-1.0More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.560nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127SMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:Displacement of [3H]U 69593 from rat recombinant kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in Y272FMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Displacement of [3H]methyl-spiperone from human recombinant D2S receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Concentration required to inhibit the action of protein phosphatase 2AMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in D208AMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Concentration required to inhibit the action of protein phosphatase 2AMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in C127SMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of [3H]nisoxetine from human recombinant norepinephrine transporter expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I](+/-)DOI from human recombinant 5-HT2B receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against partially purified (chicken skeletal muscle) Protein phosphatase 2AMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]NKA from human recombinant tachykinin NK2 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac)More data for this Ligand-Target Pair