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Found 918 with Last Name = 'salvatore' and Initial = 'c'
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataKi:  0.00500nMAssay Description:Displacement of [125I]CGRP from human cloned CLR/RAMP1 receptor expressed in E10 cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356281(CHEMBL1910953)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356281(CHEMBL1910953)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cells after 3 hrsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50385312(CHEMBL2035984)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]CGRP from human recombinant CALCRL/RAMP1 receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50385311(CHEMBL2035985)
Affinity DataKi:  0.0160nMAssay Description:Displacement of [125I]CGRP from human recombinant CALCRL/RAMP1 receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440788(CHEMBL2431249)
Affinity DataKi:  0.0170nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440782(CHEMBL2431246)
Affinity DataKi:  0.0190nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356282(CHEMBL1910936)
Affinity DataKi:  0.0210nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440784(CHEMBL2431253)
Affinity DataKi:  0.0210nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50356282(CHEMBL1910936)
Affinity DataKi:  0.0220nMAssay Description:Displacement of [125I]CGRP from human recombinant CALCRL/RAMP1 receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440791(CHEMBL2431256)
Affinity DataKi:  0.0220nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50315401((R)-1-((2'-oxo-1',2',6,8-tetrahydrospiro[cyclopent...)
Affinity DataKi:  0.0230nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50356282(CHEMBL1910936)
Affinity DataKi:  0.0240nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50385313(CHEMBL2035982)
Affinity DataKi:  0.0280nMAssay Description:Displacement of [125I]CGRP from human recombinant CALCRL/RAMP1 receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440793(CHEMBL2431254)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301971(2-((S)-6-(2,6-difluorophenyl)-3,3-dimethyl-2-oxopi...)
Affinity DataKi:  0.0350nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342639(CHEMBL1770729 | N-((6S,9R)-6-(2,3-difluorophenyl)-...)
Affinity DataKi:  0.0360nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329174(CHEMBL1269644 | N-(((R)-2,3-dihydro-1H-inden-1-yl)...)
Affinity DataKi:  0.0370nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342638(CHEMBL1770728 | N-((6S,9R)-6-(2,3-difluorophenyl)-...)
Affinity DataKi:  0.0390nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50254445((S)-2-(2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5...)
Affinity DataKi:  0.0390nMAssay Description:Displacement of [125I]human CGRP from human CLR expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50254445((S)-2-(2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50254445((S)-2-(2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342625(CHEMBL1770715 | N-((6S,9R)-6-(2,3-difluorophenyl)-...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385314(CHEMBL2035981)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50385314(CHEMBL2035981)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]CGRP from human recombinant CALCRL/RAMP1 receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50444982(CHEMBL3099918)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440786(CHEMBL2431251)
Affinity DataKi:  0.0450nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440789(CHEMBL2431248)
Affinity DataKi:  0.0460nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50385309(CHEMBL2035983)
Affinity DataKi:  0.0470nMAssay Description:Displacement of [125I]CGRP from human recombinant CALCRL/RAMP1 receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342636(CHEMBL1770726 | N-((6S,9R)-6-(2,3-difluorophenyl)-...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50444972(CHEMBL3099931)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM103499(US8552023, 11)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342634(CHEMBL1770724 | N-((6S,9R)-6-(2,3-difluorophenyl)-...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385309(CHEMBL2035983)
Affinity DataKi:  0.0520nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440790(CHEMBL2431247)
Affinity DataKi:  0.0560nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342630(CHEMBL1770720 | N-((6S,9R)-6-(2,3-difluorophenyl)-...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50315409(2a-ethyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro[...)
Affinity DataKi:  0.0720nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50444980(CHEMBL3099920)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50444984(CHEMBL3099916)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440785(CHEMBL2431252)
Affinity DataKi:  0.0940nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329172(CHEMBL1270291 | N-(((S)-2'-oxo-1',2',6,8-tetrahydr...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440792(CHEMBL2431255)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50440783(CHEMBL2429882)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]-hCGRP from human CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329175(CHEMBL1269645 | N-(((R)-2,3-dihydro-1H-inden-1-yl)...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296785((S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]human CGRP from human CLR expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50315407(2a-methyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329173(CHEMBL1270391 | N-((R)-1-(3,5-difluorophenyl)ethyl...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Department Of Medicinal Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM103501(US8552023, 13)
Affinity DataKi:  0.130nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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