TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human NK3 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-IPAG from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Binding affinity to human NK3 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Reversible Inhibition constants of the compound against IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against IL-1 beta converting enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16.9nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16.9nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17.5nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]LSD from full length rat 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement [3H]SB-222200 from of human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 22.3nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair