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Found 42 with Last Name = 'santos' and Initial = 'i'
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568077(CHEMBL4865195)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to Trypanosoma brucei rhodesainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKi:  9nMAssay Description:Competitive inhibition of VEGFR2 by qPCR methodMore data for this Ligand-Target Pair
TargetCruzipain(Trypanosoma cruzi)
Federal University of Sao Paulo

LigandPNGBDBM241952(Fukugetin)
Affinity DataKi:  1.00E+3nMAssay Description:To characterize the type and extent inhibition of papain by fukugetin, papain (0.04 nM) was incubated with four concentrations of fukugetin (1.5, 3, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidade De Lisboa

LigandPNGBDBM166688(2-Amino-2-(aminomethyl)-6-(1-carboxy-4-(2-nitrogua...)
Affinity DataKi:  6.20E+3nMAssay Description:The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Carica papaya)
Federal University of Sao Paulo

LigandPNGBDBM241952(Fukugetin)
Affinity DataKi:  1.34E+4nMAssay Description:To characterize the type and extent inhibition of papain by fukugetin, papain (0.04 nM) was incubated with four concentrations of fukugetin (1.5, 3, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidade De Lisboa

LigandPNGBDBM166687(2-Amino-2-(aminomethyl)-5-(3-nitroguanidino)pentan...)
Affinity DataKi:  2.94E+4nMAssay Description:The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidade De Lisboa

LigandPNGBDBM166691(4-{3-[(1-carboxylato-4-{[iminiumyl(nitroamino)meth...)
Affinity DataKi:  5.72E+4nMAssay Description:The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidade De Lisboa

LigandPNGBDBM166690(1,1,1-triformyl-4-(3-{[iminiumyl(nitroamino)methyl...)
Affinity DataKi:  2.41E+5nMAssay Description:The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidade De Lisboa

LigandPNGBDBM166692(4-{6-[(1-carboxylato-4-{[(carboxylatoamino)(iminiu...)
Affinity DataKi:  2.59E+5nMAssay Description:The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidade De Lisboa

LigandPNGBDBM166689(2-Amino-2-(aminomethyl)-9-(1-carboxy-4-(2-nitrogua...)
Affinity DataKi:  7.60E+5nMAssay Description:The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Sao Paulo

LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568076(CHEMBL4877896)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Sao Paulo

LigandPNGBDBM50568076(CHEMBL4877896)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568075(CHEMBL4845877)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568074(CHEMBL4859457)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568075(CHEMBL4845877)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568076(CHEMBL4877896)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50049066(2-Hydroxynaphthoquinone | CHEBI:44401 | Lawsone | ...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Sao Paulo

LigandPNGBDBM50568075(CHEMBL4845877)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Sao Paulo

LigandPNGBDBM50568074(CHEMBL4859457)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50568074(CHEMBL4859457)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University Of Alagoas

Curated by ChEMBL
LigandPNGBDBM50049066(2-Hydroxynaphthoquinone | CHEBI:44401 | Lawsone | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484504(CHEMBL1926773)
Affinity DataKd:  278nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484500(CHEMBL1926775)
Affinity DataKd:  192nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484500(CHEMBL1926775)
Affinity DataKd:  192nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484499(CHEMBL1926770)
Affinity DataKd:  167nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484499(CHEMBL1926770)
Affinity DataKd:  167nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484498(CHEMBL1926769)
Affinity DataKd:  91nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484498(CHEMBL1926769)
Affinity DataKd:  91nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50388976(CHEMBL2063878)
Affinity DataKd:  16nMAssay Description:Competitive inhibition of VEGFR2 by qPCR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484504(CHEMBL1926773)
Affinity DataKd:  278nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484503(CHEMBL1926774)
Affinity DataKd:  286nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484503(CHEMBL1926774)
Affinity DataKd:  286nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484502(CHEMBL1926768)
Affinity DataKd:  42nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484502(CHEMBL1926768)
Affinity DataKd:  42nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484501(CHEMBL1926771)
Affinity DataKd:  222nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50100134(2-(4-Dimethylamino-phenyl)-3,6-dimethyl-benzothiaz...)
Affinity DataKd:  384nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50100134(2-(4-Dimethylamino-phenyl)-3,6-dimethyl-benzothiaz...)
Affinity DataKd:  384nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Instituto Tecnol£Gico E Nuclear

Curated by ChEMBL
LigandPNGBDBM50484501(CHEMBL1926771)
Affinity DataKd:  222nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed