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Found 60 with Last Name = 'sattigeri' and Initial = 'v'
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435064(CHEMBL2391315)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325684((S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-diox...)
Affinity DataIC50:  100nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435063(CHEMBL2391316)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325710((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  200nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435079(CHEMBL2391321)
Affinity DataIC50:  290nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325699((S)-2-((4R,5R)-5-(cyclopropylcarbamoyl)-1,3-dioxol...)
Affinity DataIC50:  300nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435078(CHEMBL2391322)
Affinity DataIC50:  370nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325714((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  400nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435070(CHEMBL2391499)
Affinity DataIC50:  430nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325689((S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-diox...)
Affinity DataIC50:  500nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325712((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  500nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325700((S)-2-((4R,5R)-5-(benzo[d]thiazol-2-ylcarbamoyl)-1...)
Affinity DataIC50:  600nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325704((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  600nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325707((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  600nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325702((S)-2-((4R,5R)-5-(2-(1H-indol-3-yl)ethylcarbamoyl)...)
Affinity DataIC50:  600nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435077(CHEMBL2391323)
Affinity DataIC50:  690nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325713((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  700nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325705((S)-2-((4R,5R)-5-(2-chlorophenylcarbamoyl)-1,3-dio...)
Affinity DataIC50:  700nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325701((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  700nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435069(CHEMBL2391310)
Affinity DataIC50:  760nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435062(CHEMBL2391317)
Affinity DataIC50:  830nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435067(CHEMBL2391312)
Affinity DataIC50:  890nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325709((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  900nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435068(CHEMBL2391311)
Affinity DataIC50:  980nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325715((S)-2-((4R,5R)-5-(1-benzyl-3-tert-butyl-1H-pyrazol...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325694((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435075(CHEMBL2391494)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435076(CHEMBL2391493)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435058(CHEMBL2391309)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325691((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325698((S)-2-((4R,5R)-5-(tert-butylcarbamoyl)-1,3-dioxola...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325690((S)-2-((4R,5R)-5-(cyclohexylcarbamoyl)-1,3-dioxola...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435066(CHEMBL2391313)
Affinity DataIC50:  1.40E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325693((S)-2-((4R,5R)-5-(butylcarbamoyl)-1,3-dioxolane-4-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325696((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325708((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325711((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435061(CHEMBL2391318)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435074(CHEMBL2391495)
Affinity DataIC50:  1.80E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435073(CHEMBL2391496)
Affinity DataIC50:  1.90E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325692((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325716((S)-2-((4R,5R)-5-(3-tert-butyl-1-p-tolyl-1H-pyrazo...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435059(CHEMBL2391320)
Affinity DataIC50:  2.70E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325681((S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-diox...)
Affinity DataIC50:  2.70E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435060(CHEMBL2391319)
Affinity DataIC50:  2.70E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325706((S)-2-((4R,5R)-5-(4-chlorophenylcarbamoyl)-1,3-dio...)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435065(CHEMBL2391314)
Affinity DataIC50:  2.90E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325703((S)-2-((4R,5R)-5-(benzo[d][1,3]dioxol-5-ylmethylca...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
New Drug Discovery Research

Curated by ChEMBL
LigandPNGBDBM50325717((S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)...)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of VCAM1 from VLA4 receptor in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50435072(CHEMBL2391497)
Affinity DataIC50:  3.50E+3nMAssay Description:Antagonist activity at VLA-4 receptor in human U937 cells assessed as inhibition of VCAM-1 binding by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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