Affinity DataKi: 0.389nM IC50: 0.837nMAssay Description:The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...More data for this Ligand-Target Pair
Affinity DataKi: 0.440nM ΔG°: -54.3kJ/mole IC50: 0.948nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
Affinity DataKi: 0.458nM ΔG°: -54.2kJ/mole IC50: 0.986nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
Affinity DataKi: 0.549nM ΔG°: -53.7kJ/mole IC50: 1.18nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
Affinity DataKi: 0.662nM IC50: 1.43nMAssay Description:The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...More data for this Ligand-Target Pair
Affinity DataKi: 0.680nM ΔG°: -53.2kJ/mole IC50: 1.46nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
Affinity DataKi: 0.685nM IC50: 1.48nMAssay Description:The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...More data for this Ligand-Target Pair
Affinity DataKi: 2.14nM IC50: 4.61nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
Affinity DataKi: 2.14nM IC50: 46.1nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
Affinity DataKi: 3.26nM IC50: 7.02nMAssay Description:The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...More data for this Ligand-Target Pair
Affinity DataKi: 7.70nM IC50: 16.6nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
Affinity DataKi: 7.97nM ΔG°: -47.0kJ/mole IC50: 17.2nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
Affinity DataKi: 11.1nM IC50: 23.9nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
Affinity DataKi: 35.7nM IC50: 76.9nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
Affinity DataKi: 60nM IC50: 13nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
Affinity DataKi: 68.4nM IC50: 147nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
Affinity DataKi: 222nM IC50: 477nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
Affinity DataKi: 237nM IC50: 510nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
Affinity DataKi: 372nM IC50: 801nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
Affinity DataIC50: 0.227nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.293nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.645nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.740nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
Affinity DataIC50: 4.19nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
Affinity DataIC50: 5.01nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Determination of antagonistic activity of compounds of general formula 1 towards 5-HT6 receptors. Compounds of general formula 1 were tested for thei...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out by method of radioligand ...More data for this Ligand-Target Pair
Affinity DataIC50: 11.3nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...More data for this Ligand-Target Pair