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Found 64 with Last Name = 'sawyer' and Initial = 'da'
TargetInositol polyphosphate-5-phosphatase A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50279840((D)-2,2-difluoro-2-deoxy-myo-inositol 1,4,5-tripho...)
Affinity DataKi:  2.60E+4nMAssay Description:Compound was evaluated for binding affinity towards Inositol-1,4,5-trisphosphate 5-phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetInositol 1,4,5-trisphosphate receptor type 1/2/3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50211666(CHEMBL1161456)
Affinity DataKi:  2.92E+5nMAssay Description:Compound was evaluated for its ability to inhibit Inositol phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086462((S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086466((S)-3-(2-Acetimidoylamino-ethoxy)-2-amino-propioni...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086459(4-(2-Acetimidoylamino-ethoxy)-2-amino-butyric acid...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035267(CHEMBL66344 | [2-(4-Decyloxy-3,5-dimethoxy-benzoyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035258(CHEMBL66185 | [4-(4-Decyloxy-3,5-dimethoxy-benzoyl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035259(CHEMBL67302 | [4-(4-Hexadecyloxy-3,5-dimethoxy-ben...)
Affinity DataIC50:  2.90E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086461((R)-3-(2-acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086470((R)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086459(4-(2-Acetimidoylamino-ethoxy)-2-amino-butyric acid...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50230993((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086468((S)-3-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086464((S)-3-(2-Acetimidoylamino-ethanesulfonyl)-2-amino-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035262(CHEMBL67232 | [4-(3-Chloro-4-hexyloxy-5-methoxy-be...)
Affinity DataIC50:  9.60E+3nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086466((S)-3-(2-Acetimidoylamino-ethoxy)-2-amino-propioni...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035264(CHEMBL70229 | {2-[4-(4-Hexyloxy-3,5-dimethoxy-benz...)
Affinity DataIC50:  1.18E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035260(CHEMBL307760 | [4-(4-Hexyloxy-3,5-dimethyl-benzoyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086466((S)-3-(2-Acetimidoylamino-ethoxy)-2-amino-propioni...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086462((S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035266(5-[4-(4-Hexyloxy-3,5-dimethoxy-phenyl)-butyl]-4-me...)
Affinity DataIC50:  1.35E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035263(CHEMBL66234 | [4-(3,5-Dimethoxy-4-octyloxy-benzoyl...)
Affinity DataIC50:  1.38E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035265(CHEMBL67396 | [2-(4-Hexyloxy-3,5-dimethoxy-benzoyl...)
Affinity DataIC50:  1.60E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50030276(7-Acetimidoylamino-2-amino-heptanoic acid | CHEMBL...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035257(CHEMBL67031 | [4-(4-Hexyloxy-benzoyloxy)-butyl]-tr...)
Affinity DataIC50:  2.25E+4nMAssay Description:Activity against adenosine diphosphate (ADP) induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086462((S)-3-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  4.00E+4nMAssay Description:Concentration required for inhibition of endothelial Nitric Oxide Synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086461((R)-3-(2-acetimidoylamino-ethylsulfanyl)-2-amino-p...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086465((R)-3-(3-Acetimidoylamino-propylsulfanyl)-2-amino-...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086468((S)-3-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086459(4-(2-Acetimidoylamino-ethoxy)-2-amino-butyric acid...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50030277((R)-6-Acetimidoylamino-2-amino-hexanoic acid | CHE...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086471((S)-3-(3-Acetimidoylamino-propoxy)-2-amino-propion...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086463((R)-3-(3-Acetimidoylamino-propane-1-sulfonyl)-2-am...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086465((R)-3-(3-Acetimidoylamino-propylsulfanyl)-2-amino-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086470((R)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086463((R)-3-(3-Acetimidoylamino-propane-1-sulfonyl)-2-am...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086471((S)-3-(3-Acetimidoylamino-propoxy)-2-amino-propion...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086469(4-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50030276(7-Acetimidoylamino-2-amino-heptanoic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human neuronal Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086460(4-(2-Acetimidoylamino-ethanesulfonyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086465((R)-3-(3-Acetimidoylamino-propylsulfanyl)-2-amino-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086463((R)-3-(3-Acetimidoylamino-propane-1-sulfonyl)-2-am...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086460(4-(2-Acetimidoylamino-ethanesulfonyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for inhibition of neuronal Nitric Oxide Synthase in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50030276(7-Acetimidoylamino-2-amino-heptanoic acid | CHEMBL...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human endothelial Nitric Oxide SynthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50086469(4-(2-Acetimidoylamino-ethanesulfinyl)-2-amino-buty...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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