TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 0.000340nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Inhibition of human TS by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.17E+3nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 4.33E+3nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 4.68E+3nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Universita` Degli Studi Di Sassari
Curated by ChEMBL
Affinity DataKi: 1.54E+4nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Mixed-type inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+4nMAssay Description:Inhibition of human TS by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.80E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of His-tagged human thymidylate synthase L198A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of His-tagged human thymidylate synthase F59A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of His-tagged human thymidylate synthase F59A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of His-tagged human thymidylate synthase F59A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of His-tagged human thymidylate synthase F59A mutant after 1 hr by UV-visible spectrophotometryMore data for this Ligand-Target Pair