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Found 70 with Last Name = 'saywell' and Initial = 'k'
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50:  2nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50:  2nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035373(7-Chloro-2-(4-methoxy-phenyl)-3,5-dihydro-2H-pyraz...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035367(7-Chloro-2-phenyl-3,5-dihydro-2H-pyrazolo[3,4-c]qu...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50285191(4-Hydroxy-7-methyl-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056659(CHEMBL165371 | [7-Chloro-2-oxo-3-(3-phenoxy-phenyl...)
Affinity DataIC50:  24nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50280269(3-[2-(4-Amino-benzylcarbamoyl)-ethyl]-4,6-dichloro...)
Affinity DataIC50:  27nMAssay Description:Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061396(4,6-Dichloro-3-(2-phenylcarbamoyl-ethyl)-1H-indole...)
Affinity DataIC50:  36nMAssay Description:Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50285192(4-Hydroxy-7-methyl-3-(3-phenoxy-phenyl)-5,6,7,8-te...)
Affinity DataIC50:  57nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004952(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)
Affinity DataIC50:  70nMAssay Description:Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035374(2-(4-Methoxy-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c...)
Affinity DataIC50:  87nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035370(3-Methyl-2-phenyl-3,5-dihydro-2H-pyrazolo[3,4-c]qu...)
Affinity DataIC50: >100nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056667((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Affinity DataIC50:  110nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035375(2-Phenyl-3,5-dihydro-2H-pyrazolo[3,4-c]quinoline-1...)
Affinity DataIC50:  135nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035372(2-(4-Chloro-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c]...)
Affinity DataIC50:  138nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056663((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Affinity DataIC50:  160nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035371(2-(3-Chloro-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c]...)
Affinity DataIC50:  162nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041467(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Affinity DataIC50:  170nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056673(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Affinity DataIC50:  170nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50041467(7-Chloro-4-hydroxy-3-phenyl-1H-quinolin-2-one | 7-...)
Affinity DataIC50:  170nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056657(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Affinity DataIC50:  190nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056653(7-Chloro-3-phenyl-4-[2-(1H-tetrazol-5-yl)-ethyl]-1...)
Affinity DataIC50:  240nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056652(CHEMBL351884 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Affinity DataIC50:  270nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056645((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Affinity DataIC50:  320nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056672(4-Amino-7-chloro-3-(3-phenoxy-phenyl)-1H-quinolin-...)
Affinity DataIC50:  420nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056654(2-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Affinity DataIC50:  420nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056661(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Affinity DataIC50:  500nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035369(2-Benzyl-3,5-dihydro-2H-pyrazolo[3,4-c]quinoline-1...)
Affinity DataIC50:  562nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056656(CHEMBL166246 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Affinity DataIC50:  580nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035368(2-(2-Chloro-phenyl)-3,5-dihydro-2H-pyrazolo[3,4-c]...)
Affinity DataIC50:  613nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056671(3-(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-...)
Affinity DataIC50:  750nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056647(7-Chloro-4-{2-[(E)-hydroxyimino]-propoxy}-3-phenyl...)
Affinity DataIC50:  780nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50280277(3-Carbamoyl-6-chloro-1H-indole-2-carboxylic acid |...)
Affinity DataIC50:  810nMAssay Description:Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056639(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinoline-4-ca...)
Affinity DataIC50:  900nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056644(CHEMBL164831 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056637((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056665(CHEMBL433908 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Affinity DataIC50:  1.19E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056648(CHEMBL164184 | [7-Chloro-2-oxo-3-(3-phenoxy-phenyl...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056643(7-Chloro-4-(2-oxo-propoxy)-3-phenyl-1H-quinolin-2-...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009079(6-Chloro-3-methoxycarbonylmethyl-1H-indole-2-carbo...)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of [3H]-L-689,560 binding to Glycine site of NMDA receptor of rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056641(4-Benzylamino-7-chloro-3-phenyl-1H-quinolin-2-one ...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50035376(2-Methyl-3,5-dihydro-2H-pyrazolo[3,4-c]quinoline-1...)
Affinity DataIC50:  2.02E+3nMAssay Description:Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slicesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056666(CHEMBL352889 | N-(7-Chloro-2-oxo-3-phenyl-1,2-dihy...)
Affinity DataIC50:  2.70E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056638(7-Chloro-3-phenyl-4-(pyridin-2-ylmethoxy)-1H-quino...)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056642((7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinolin-4-yl...)
Affinity DataIC50:  3.20E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056649(7-Chloro-4-(2-dimethylamino-ethylamino)-3-phenyl-1...)
Affinity DataIC50:  3.20E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056651(7-Chloro-4-[2-(3-methyl-[1,2,4]oxadiazol-5-yl)-eth...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50285189(4-Hydroxy-7-methyl-3-phenyl-5,6,7,8-tetrahydro-1H-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056662(7-Chloro-4-(3-dimethylamino-propylamino)-3-phenyl-...)
Affinity DataIC50:  4.20E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056669(4-Amino-7-chloro-3-phenyl-1H-quinolin-2-one | CHEM...)
Affinity DataIC50:  6.70E+3nMAssay Description:In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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