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Found 33 with Last Name = 'scala' and Initial = 'a'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat cerebral cortex glutamate NMDA receptor GluN2B subunit after 120 mins by scintillation counting analys...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50276976(2-(4-benzylpiperidin-1-yl)-1-(5-hydroxy-1Hindol-3-...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat cerebral cortex glutamate NMDA receptor GluN2B subunit after 120 mins by scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444775(CHEMBL3099037)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444776(CHEMBL3099036)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444778(CHEMBL3099035)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444771(CHEMBL3099053)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444772(CHEMBL3099052)
Affinity DataKi:  557nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444777(CHEMBL456206)
Affinity DataKi:  1.67E+3nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat cerebral cortex glutamate NMDA receptor GluN2B subunit after 120 mins by scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444779(CHEMBL3099034)
Affinity DataKi:  1.91E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444774(CHEMBL3099050)
Affinity DataKi:  2.68E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444773(CHEMBL3099051)
Affinity DataKi:  3.08E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50276976(2-(4-benzylpiperidin-1-yl)-1-(5-hydroxy-1Hindol-3-...)
Affinity DataKi:  4.73E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50444777(CHEMBL456206)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from guinea pig brain sigma1 receptor after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50089541((R)-[(S)-(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae after 90 mins in presence of trypsinMore data for this Ligand-Target Pair
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50089541((R)-[(S)-(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]-N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  30nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  40nMAssay Description:Inhibition of cathepsin B (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50231813((2S,4aR,6aS,6bR,8aR,9R,10R,11S,12aR,12bR,14bS)-11-...)
Affinity DataIC50: >400nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChitin synthase 1(Saccharomyces cerevisiae)
Universidad Nacional De Rosario

Curated by ChEMBL
LigandPNGBDBM50231813((2S,4aR,6aS,6bR,8aR,9R,10R,11S,12aR,12bR,14bS)-11-...)
Affinity DataIC50: >400nMAssay Description:Inhibition of chitin synthase 1 in Saccharomyces cerevisiae assessed as incorporation of [14C]-N-Acetylglucosamine after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032157(CHEMBL3360923)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032226(CHEMBL3352911)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032157(CHEMBL3360923)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032159(CHEMBL3352912)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of cathepsin B (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032159(CHEMBL3352912)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032226(CHEMBL3352911)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032240(CHEMBL3352910)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of cathepsin B (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032240(CHEMBL3352910)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032159(CHEMBL3352912)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032157(CHEMBL3360923)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cathepsin B (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032226(CHEMBL3352911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cathepsin B (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universidade Federal De S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50032240(CHEMBL3352910)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorometric Z-Phe-Arg-AMC as substrate by spectrofluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed