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Found 45 with Last Name = 'scala' and Initial = 's'
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250705(CHEMBL4078698)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250704(CHEMBL4089168)
Affinity DataIC50:  6nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250733(CHEMBL4064373)
Affinity DataIC50:  6nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250704(CHEMBL4089168)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250710(CHEMBL4061034)
Affinity DataIC50:  22nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  40nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  53nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  53nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  64nMAssay Description:Inhibition of 12G5 anti-CXCR4 antibody binding to CXCR4 in human HT29 cells preincubated for 30 mins followed by antibody addition by FACS Canto II c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250721(CHEMBL4093767)
Affinity DataIC50:  70nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192651(CHEMBL3980379)
Affinity DataIC50:  131nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250732(CHEMBL4064578)
Affinity DataIC50:  180nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250711(CHEMBL4065967)
Affinity DataIC50:  210nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  338nMAssay Description:Displacement of [125I]-CXCL12 from CXCR4 in human CCRF-CEM cells after 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250709(CHEMBL4076358)
Affinity DataIC50:  360nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192646(CHEMBL3916038)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250708(CHEMBL4079246)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250723(CHEMBL4060078)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250706(CHEMBL4096721)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250725(CHEMBL4073066)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50244994(CHEMBL4092239)
Affinity DataIC50:  3.20E+3nMAssay Description:Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of PE-conjugated 12G5 antibody bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250724(CHEMBL4074277)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of 12G5 anti-CXCR4 antibody binding to CXCR4 in human HT29 cells preincubated for 30 mins followed by antibody addition by FACS Canto II c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192650(CHEMBL3981298)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192645(CHEMBL3952526)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50244998(CHEMBL4064541)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of PE-conjugated 12G5 antibody bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50244997(CHEMBL4070596)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity at [3H]CD radiolabeled muscarinic M2 receptor in rat cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50244996(CHEMBL4101762)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of PE-conjugated 12G5 antibody bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50244995(CHEMBL4083765)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of PE-conjugated 12G5 antibody bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250707(CHEMBL4104439)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250731(CHEMBL4091892)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50250722(CHEMBL4087597)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of anti-CXCR4 PE antibody clone 12G5 binding to CXCR4 in human CCRF-CEM cells preincubated for 30 mins followed by anti-CXCR4 PE antibody ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192653(CHEMBL3906404)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192649(CHEMBL3896351)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192648(CHEMBL3942287)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192647(CHEMBL3977069)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192644(CHEMBL3914285)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192643(CHEMBL3951019)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192642(CHEMBL3924369)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192641(CHEMBL3933305)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50244999(CHEMBL4094209)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at CXCR4 in human CCRF-CEM cells assessed as inhibition of PE-conjugated 12G5 antibody bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
University of Campania

Curated by ChEMBL
LigandPNGBDBM50192640(CHEMBL3927148)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed