Found 384 with Last Name = 'schaefer' and Initial = 'm' TargetEpidermal growth factor receptor(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
Affinity DataKi: 81.5nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 99nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR wild type (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells insec...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 142nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 wild type (679 to 1255 residues) expressed in baculovirus infected Sf9 insect cells using ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 224nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 241nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 256nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
3D Structure (crystal)TargetEpidermal growth factor receptor(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 271nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR wild type (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells insec...More data for this Ligand-Target Pair
Affinity DataKi: 347nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 434nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR wild type (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells insec...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
The State University Of New York
Curated by ChEMBL
The State University Of New York
Curated by ChEMBL
Affinity DataKi: 437nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 wild type (679 to 1255 residues) expressed in baculovirus infected Sf9 insect cells using ...More data for this Ligand-Target Pair
Affinity DataKi: 444nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 594nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 630nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 899nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 904nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 999nMAssay Description:Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.61E+3nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.13E+3nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.54E+3nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.11E+3nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.62E+3nMAssay Description:Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.19E+3nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.17E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.35E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.51E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.94E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.26E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysisMore data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 1 [C171Q](Mycobacterium tuberculosis)
University of Wuerzburg
University of Wuerzburg
Affinity DataKi: 3.84E+5nMpH: 8.5Assay Description:Binding of TLM18 to wild-type and mutant KasA was quantified by monitoring changes in the intrinsic tryptophan fluorescence of the enzyme at waveleng...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Antagonistic activity against monkey C-C chemokine receptor type 5.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Antagonistic activity against human C-C chemokine receptor type 5.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Antagonistic activity against monkey C-C chemokine receptor type 5.More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
