Compile Data Set for Download or QSAR
maximum 50k data
Found 135 with Last Name = 'schafer' and Initial = 'k'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326858(CHEMBL1254556 | N-((3R,4R,5S,6R)-2,4-bis(4-chlorob...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326859(CHEMBL1254630 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326860(CHEMBL1254711 | N-((3R,4R,5S,6R)-2-(4-chlorobenzyl...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326861(CHEMBL1254796 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326862(4-(diaminomethyleneamino)-N-((3R,4R,5S,6R)-5-hydro...)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326863(3-(diaminomethyleneamino)-N-((3R,4R,5S,6R)-5-hydro...)
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326864(CHEMBL1254883 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82341(hnpsPLA2-IIa Inhibitor, 2l)
Affinity DataIC50:  19nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82331(hnpsPLA2-IIa Inhibitor, 2b)
Affinity DataIC50:  29nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82342(hnpsPLA2-IIa Inhibitor, 2m)
Affinity DataIC50:  39nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326854((Naphth-2-yl)methyl-2-(4'-Aminobutyrylamido)-3-O-(...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82340(hnpsPLA2-IIa Inhibitor, 2k)
Affinity DataIC50:  57nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM50055341(CHEMBL149502 | [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-ME...)
Affinity DataIC50:  60nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82339(hnpsPLA2-IIa Inhibitor, 2j)
Affinity DataIC50:  67nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326878((2R,3S,5R)-5-(3-aminopropylamino)-4-(4-chlorobenzy...)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326872(CHEMBL1254140 | Naphth-2-yl)methyl-2-(4'-Aminobuty...)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82345(hnpsPLA2-IIa Inhibitor, 2p)
Affinity DataIC50:  86nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326879((2R,3S,5R)-5-(2-aminoethylamino)-2-(methoxymethyl)...)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82343(hnpsPLA2-IIa Inhibitor, 2n)
Affinity DataIC50:  116nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326865((4'-Chlorobenzyl)3-O-(4'-Chlorobenzyl)-2-deoxy-2-(...)
Affinity DataIC50:  120nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214726(Cyanines, 9)
Affinity DataIC50:  120nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326880((2R,3S,5R)-5-(2-aminoethylamino)-4-(benzyloxy)-2-(...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326881((2R,3S,5R)-5-(2-aminoethylamino)-2-(methoxymethyl)...)
Affinity DataIC50:  160nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214732(Rhodanines, 20A)
Affinity DataIC50:  170nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82344(hnpsPLA2-IIa Inhibitor, 2o)
Affinity DataIC50:  170nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214733(Rhodanines, 21A)
Affinity DataIC50:  170nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326856(4-amino-N-((2R,3R,4R,5S,6R)-5-hydroxy-6-(methoxyme...)
Affinity DataIC50:  180nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326874(CHEMBL1254882 | N-((2S,3R,4S,5S,6R)-6-(benzyloxyme...)
Affinity DataIC50:  180nMAssay Description:Displacement of [125I]iodotyrosyl from human SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326857((Naphth-2-yl)methyl-2-(3'-Aminopropionylamido)-2-d...)
Affinity DataIC50:  200nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326855(4-amino-N-((2S,3R,4S,5S,6R)-5-hydroxy-6-(methoxyme...)
Affinity DataIC50:  200nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326882((2R,3S,5R)-5-(3-aminopropylamino)-2-(methoxymethyl...)
Affinity DataIC50:  200nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214734(Rhodanines, 22A)
Affinity DataIC50:  210nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82337(hnpsPLA2-IIa Inhibitor, 2h)
Affinity DataIC50:  214nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214735(Rhodanines, 23A)
Affinity DataIC50:  230nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214737(Rhodanines, 25A)
Affinity DataIC50:  240nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214736(Rhodanines, 24A)
Affinity DataIC50:  240nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
University of Queensland Brisbane

LigandPNGBDBM82338(hnpsPLA2-IIa Inhibitor, 2i)
Affinity DataIC50:  247nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214738(Rhodanines, 26A)
Affinity DataIC50:  260nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM32329((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-...)
Affinity DataIC50:  280nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM32299(2-[(2Z)-2-[(2E)-2-[[3-(2-hydroxyethyl)-5-methoxy-1...)
Affinity DataIC50:  290nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326857((Naphth-2-yl)methyl-2-(3'-Aminopropionylamido)-2-d...)
Affinity DataIC50:  380nMAssay Description:Displacement of [125I]iodotyrosyl from human SST3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214739(Rhodanines, 27A)
Affinity DataIC50:  420nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326873(3-amino-N-((2S,3R,4S,5S,6R)-6-((4-chlorobenzyloxy)...)
Affinity DataIC50:  430nMAssay Description:Displacement of [125I]iodotyrosyl from human SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326854((Naphth-2-yl)methyl-2-(4'-Aminobutyrylamido)-3-O-(...)
Affinity DataIC50:  430nMAssay Description:Displacement of [125I]iodotyrosyl from human SST3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326875(3-amino-N-((2S,3R,4S,5S,6R)-5-hydroxy-2-(methylthi...)
Affinity DataIC50:  440nMAssay Description:Displacement of [125I]iodotyrosyl from human SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326869(4'-Chlorobenzyl-2-Deoxy-2-(4'-guanidinobutyrylamid...)
Affinity DataIC50:  450nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214740(Rhodanines, 28A)
Affinity DataIC50:  470nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM50052802(CHEBI:77181 | CRYSTAL VIOLET | Crystal violet (15)...)
Affinity DataIC50:  490nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Alchemia

Curated by ChEMBL
LigandPNGBDBM50326872(CHEMBL1254140 | Naphth-2-yl)methyl-2-(4'-Aminobuty...)
Affinity DataIC50:  500nMAssay Description:Displacement of [125I]iodotyrosyl from human SST3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM214729(Malachite green (16))
Affinity DataIC50:  520nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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