Affinity DataIC50: 10nMAssay Description:Binding affinity of second enantiomer (E2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding affinity of first enantiomer (E1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Binding affinity of first diastereomer (D1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Binding affinity of second enantiomer (E2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity of second enantiomer (E2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity of second diastereomer (D2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Binding affinity of first diastereomer (D1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Binding affinity of second enantiomer (E2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity of first enantiomer (E1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity of first diastereomer (D1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Tested for its ability to inhibit cAMP production in human glucagon receptor expressed CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Binding affinity of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Tested for its ability to inhibit cAMP production in human glucagon receptor expressed CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Binding affinity of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Binding affinity of first enantiomer (E1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Tested for its ability to inhibit cAMP production in human glucagon receptor expressed CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity of second diastereomer (D2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity of first enantiomer (E1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity of second diastereomer (D2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity of first diastereomer (D1) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against binding to the human glucagon receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration of the compound against cAMP production in hGR-CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Binding affinity of second diastereomer (D2) of the compound against human glucagon receptor was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Staphylococcus epidermidis (strain ATCC 35984 / RP...)
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Antibacterial activity against D-alanyl-D-alanine ligase from Streptococcus faecalis (ATCC 8043)More data for this Ligand-Target Pair