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Found 50 with Last Name = 'schoenfelder' and Initial = 'a'
Target4-aminobutyrate aminotransferase, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021645((3-Phenyl-thioureido)-acetic acid | CHEMBL311337 |...)
Affinity DataKi:  9.10E+4nMAssay Description:Compound was tested for inhibition of Gamma-amino-N-butyrate transaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-hydroxybutyrate receptor(RAT)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023573(4-Cyclohexyl-4-hydroxy-but-2-enoic acid | CHEMBL17...)
Affinity DataIC50:  3.30nMAssay Description:Binding affinity towards [3H]-GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-hydroxybutyrate receptor(RAT)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023572(CHEMBL354804 | Sodium; 4-hydroxy-but-2-enoate)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity towards [3H]-GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383031(CHEMBL2031290)
Affinity DataIC50:  5nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  7nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGamma-hydroxybutyrate receptor(RAT)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023574(4-Hydroxy-pent-2-enoic acid | CHEMBL171595)
Affinity DataIC50:  11nMAssay Description:Binding affinity towards [3H]-GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383020(CHEMBL2031277)
Affinity DataIC50:  13nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383029(CHEMBL2031288)
Affinity DataIC50:  14nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383031(CHEMBL2031290)
Affinity DataIC50:  15nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383020(CHEMBL2031277)
Affinity DataIC50:  24nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383015(CHEMBL2031263)
Affinity DataIC50:  29nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383028(CHEMBL2031287)
Affinity DataIC50:  33nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383016(CHEMBL2031268)
Affinity DataIC50:  41nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383016(CHEMBL2031268)
Affinity DataIC50:  63nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50:  64nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383030(CHEMBL2031289)
Affinity DataIC50:  70nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383024(CHEMBL2031283)
Affinity DataIC50:  70nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383022(CHEMBL2031077)
Affinity DataIC50:  80nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383036(CHEMBL2031098)
Affinity DataIC50:  90nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383037(CHEMBL2031245)
Affinity DataIC50:  100nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50:  107nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383021(CHEMBL2031281)
Affinity DataIC50:  110nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383032(CHEMBL2031291)
Affinity DataIC50:  110nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383041(CHEMBL2031267)
Affinity DataIC50:  130nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50249519(CHEMBL480889 | N-((3S,5S)-1-(benzo[d][1,3]dioxol-5...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50:  160nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383019(CHEMBL2031273)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at Smo receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383042(CHEMBL2031295)
Affinity DataIC50:  160nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383038(CHEMBL2031253)
Affinity DataIC50:  180nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383014(CHEMBL2031258)
Affinity DataIC50:  190nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383035(CHEMBL2031294)
Affinity DataIC50:  190nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383025(CHEMBL2031284)
Affinity DataIC50:  220nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383023(CHEMBL2031282)
Affinity DataIC50:  290nMAssay Description:Antagonist activity at Smo receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383023(CHEMBL2031282)
Affinity DataIC50:  290nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)
Affinity DataIC50:  300nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50:  300nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383033(CHEMBL2031292)
Affinity DataIC50:  370nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383017(CHEMBL2031080)
Affinity DataIC50:  520nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383026(CHEMBL2031285)
Affinity DataIC50:  640nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)
Affinity DataIC50:  650nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383034(CHEMBL2031084)
Affinity DataIC50:  650nMAssay Description:Antagonist activity at Smo receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383039(CHEMBL2031254)
Affinity DataIC50:  820nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383027(CHEMBL2031286)
Affinity DataIC50:  900nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383040(CHEMBL2031256)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383018(CHEMBL2031079)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50049748((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...)
Affinity DataIC50:  4.10E+3nMAssay Description:Compound was tested for its ability to displace metabotropic glutamate binding to rat brain membranes using [3H]glutamate radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50470991(CHEMBL353177)
Affinity DataIC50:  4.20E+3nMAssay Description:Compound was tested for its ability to displace metabotropic glutamate binding to rat brain membranes using [3H]glutamate radioligand.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGamma-hydroxybutyrate receptor(RAT)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50023575(4-hydroxy-butyric acid | 4-hydroxybutanoic acid | ...)
Affinity DataIC50:  6.60E+3nMAssay Description:Binding affinity towards [3H]-GHB binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Centre De Neurochimie Du Cnrs

Curated by ChEMBL
LigandPNGBDBM50049747((2S,4R)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...)
Affinity DataIC50:  5.53E+4nMAssay Description:Compound was tested for its ability to displace metabotropic glutamate binding to rat brain membranes using [3H]glutamate radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed