Affinity DataKi: 140nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assay in presence of de...More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assay in presence of d...More data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using low concentration of enzyme by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 640nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain using high concentration of enzyme by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay in presence of DTTMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Inhibitory activity against cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Inhibitory activity against cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 7.60E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human C-terminally His6-tagged Sirt3 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 2.69E+4nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of human recombinant N-terminally GST-tagged Sirt1 expressed in Escherichia coli using ZMAL as substrate after 4 hrs by homogeneous fluore...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Ernst-Moritz-Arndt University Greifswald
Curated by ChEMBL
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of human N-terminally His6-tagged Sirt2 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assayMore data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair
TargetORF 73(Human herpesvirus 8)
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Institute For Pharmaceutical Research Saarland (Hips)-Helmholtz Centre For Infection Research (Hzi
Curated by ChEMBL
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1...More data for this Ligand-Target Pair