Affinity DataKi: 5.40E+4nMAssay Description:Competitive inhibition of Escherichia coli thymidine phosphorylase incubated for 20 mins at room temperature followed by 5 mins incubation at 90 degC...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Competitive inhibition of Escherichia coli thymidine phosphorylase incubated for 20 mins at room temperature followed by 5 mins incubation at 90 degC...More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+5nMAssay Description:Competitive inhibition of Escherichia coli thymidine phosphorylase incubated for 20 mins at room temperature followed by 5 mins incubation at 90 degC...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 5a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 4a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5' end radiolabeled 24nt DNA/48nt DNA as primer/template after 5 mins by PAGE analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human CYP3A4 using ketoconazole as substrateMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human CYP3A4 using ketoconazole as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human DNA polymerase beta using 5' end radiolabeled 24nt DNA/48nt DNA as primer/template after 5 mins by PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human DNA polymerase alpha using 5' end radiolabeled 24nt DNA/48nt DNA as primer/template after 5 mins by PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C9 using sulfaphenazole as substrateMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole-cell patch clamp assayMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Emory University School Of Medicine
Curated by ChEMBL
Emory University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysisMore data for this Ligand-Target Pair