Found 206 with Last Name = 'scilimati' and Initial = 'a' 
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin addition meas...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Bari "A. Moro
Curated by ChEMBL
University Of Bari "A. Moro
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged FPPS expressed in Escherichia coli BL21 using DMAPP and IPP as substrates pretreated for 15 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Bari "A. Moro
Curated by ChEMBL
University Of Bari "A. Moro
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged FPPS expressed in Escherichia coli BL21 using DMAPP and IPP as substrates pretreated for 15 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 99nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of COX-2 in human whole blood assessed as inhibition of LPS-induced plasma PGE2 level by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human COX2 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of ovine COX2 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of COX-1 in human washed platelet assessed as inhibition of 0.5 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Bari "A. Moro
Curated by ChEMBL
University Of Bari "A. Moro
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged FPPS expressed in Escherichia coli BL21 using DMAPP and IPP as substrates pretreated for 15 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of ovine COX-2 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of COX-1 in human whole blood assessed as inhibition of serum TXB2 level after 1 hr by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of LPS-induced COX1 in human whole blood assessed as reduction in TXB2 levels by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
