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Found 360 with Last Name = 'scott' and Initial = 've'
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86244(A-312110)
Affinity DataKi:  4.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86250(CAS_60559-98-0 | NSC_43345 | P1075)
Affinity DataKi:  10.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86250(CAS_60559-98-0 | NSC_43345 | P1075)
Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86247(BAY X 9228 | CAS_3038059 | NSC_3038059)
Affinity DataKi:  16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86250(CAS_60559-98-0 | NSC_43345 | P1075)
Affinity DataKi:  20.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86247(BAY X 9228 | CAS_3038059 | NSC_3038059)
Affinity DataKi:  41.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50110068(3-Chloro-4-hydroxy-benzoic acid [1-[4-(4-isopropyl...)
Affinity DataKi:  56nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50122102(3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetrame...)
Affinity DataKi:  72nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374178(CHEMBL411120)
Affinity DataKi:  85nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86245(CAS_85371-64-8 | NSC_4826 | PINACIDIL)
Affinity DataKi:  104nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374184(CHEMBL270677)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374179(CHEMBL409325)
Affinity DataKi:  152nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86251(CAS_94535-50-9 | CROMAKALIM (-) | NSC_93504)
Affinity DataKi:  157nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374188(CHEMBL270226)
Affinity DataKi:  167nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374187(CHEMBL256379)
Affinity DataKi:  185nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374177(CHEMBL409729)
Affinity DataKi:  204nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374180(CHEMBL404071)
Affinity DataKi:  241nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86245(CAS_85371-64-8 | NSC_4826 | PINACIDIL)
Affinity DataKi:  251nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374186(CHEMBL272122)
Affinity DataKi:  274nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374183(CHEMBL269990)
Affinity DataKi:  404nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86249(ZD 6169 | ZD-6169)
Affinity DataKi:  451nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374182(CHEMBL272118)
Affinity DataKi:  522nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374181(CHEMBL256837)
Affinity DataKi:  537nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86251(CAS_94535-50-9 | CROMAKALIM (-) | NSC_93504)
Affinity DataKi:  542nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50374185(CHEMBL255824)
Affinity DataKi:  554nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50110055(3-Chloro-4-hydroxy-benzoic acid [1-(4-isopropyl-be...)
Affinity DataKi:  604nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86249(ZD 6169 | ZD-6169)
Affinity DataKi:  630nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86246(zm244085)
Affinity DataKi:  671nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86246(zm244085)
Affinity DataKi:  2.77E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86248(CAS_364-98-7 | NSC_3019 | diazoxide)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories

Curated by PDSP Ki Database
LigandPNGBDBM86248(CAS_364-98-7 | NSC_3019 | diazoxide)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50386813(CHEMBL2047726)
Affinity DataIC50:  40.7nMAssay Description:Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50386813(CHEMBL2047726)
Affinity DataIC50:  41nMAssay Description:Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438747(CHEMBL2414787)
Affinity DataIC50:  340nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438746(CHEMBL2414771)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095305(CHEMBL1486348)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438746(CHEMBL2414771)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095306(CHEMBL3589094)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Rattus norvegicus)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of Cav3.2 channel in rat DRG neurons assessed as reduction in LVA currentsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of L-type calcium channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50438747(CHEMBL2414787)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095307(CHEMBL3589546)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095308(CHEMBL3589554)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207140(CHEMBL131352)
Affinity DataEC50:  5.01E+3nMAssay Description:In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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