TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 152nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 167nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 185nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 204nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 241nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 274nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 404nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 522nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 537nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 554nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 604nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetCalcium-activated potassium channel subunit beta(GUINEA PIG)
Abbott Laboratories
Curated by PDSP Ki Database
Abbott Laboratories
Curated by PDSP Ki Database
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 40.7nMAssay Description:Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of rat Cav2.2 expressed in HEK293 cells under inactivating depolarizing conditions at holding potential of -115mV and stepped to 0 mV once...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Rattus norvegicus)
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of Cav3.2 channel in rat DRG neurons assessed as reduction in LVA currentsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of L-type calcium channel (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Abbvie
Curated by ChEMBL
Abbvie
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 9/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 5.01E+3nMAssay Description:In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2BMore data for this Ligand-Target Pair