Compile Data Set for Download or QSAR
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Found 26 with Last Name = 'secrist' and Initial = 'pj'
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215008(4-(1,3-dioxo-1,3-bis(phenylamino)propan-2-yl)-N-hy...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215018(4-(1,3-bis(2,3-dihydrobenzo[b][1,4]dioxin-6-ylamin...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215015(4-(1,3-bis(3-cyanophenylamino)-1,3-dioxopropan-2-y...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215016(4-(1,3-bis(3-methoxyphenylamino)-1,3-dioxopropan-2...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(CHEMBL251144 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215014(4-(1,3-bis(3-morpholinophenylamino)-1,3-dioxopropa...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215013(CHEMBL398950 | N-(2-aminophenyl)-4-(3-oxo-3-(pheny...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215003(4-(1,3-bis(2-methoxyphenylamino)-1,3-dioxopropan-2...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215012(CHEMBL251756 | N-(2-aminophenyl)-4-(2-fluoro-1,3-d...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215004(4-(1,3-bis(3-fluorophenylamino)-1,3-dioxopropan-2-...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215005(4-(1,3-bis(4-fluorophenylamino)-1,3-dioxopropan-2-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215009(CHEMBL251757 | N-(2-aminophenyl)-4-(2-hydroxy-1,3-...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215011(CHEMBL400921 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50:  103nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215017(CHEMBL251544 | N-(2-aminophenyl)-4-(3-(methyl(phen...)
Affinity DataIC50:  196nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215021(CHEMBL248718 | N-(2-aminophenyl)-4-(2-methyl-1,3-d...)
Affinity DataIC50:  198nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215002(4-(1,3-bis(benzylamino)-1,3-dioxopropan-2-yl)-N-(2...)
Affinity DataIC50:  199nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215007(CHEMBL248909 | N-(2-aminophenyl)-4-(2-methyl-3-oxo...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215006(CHEMBL251546 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50:  229nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(CHEMBL251144 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50:  313nMAssay Description:Inhibition of human HDAC2 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(CHEMBL251144 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50:  697nMAssay Description:Inhibition of human HDAC3 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215019(4-tert-butyl-N-hydroxybenzamide | CHEMBL249284)
Affinity DataIC50:  715nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215020(4-(1,3-bis(methyl(phenyl)amino)-1,3-dioxopropan-2-...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(CHEMBL251144 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215010(CHEMBL251144 | N-(2-aminophenyl)-4-(1,3-dioxo-1,3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50015184(BENZHYDROXAMIC ACID | BENZOHYDROXAMATE | CHEMBL163...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099857(ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...)
Affinity DataIC50:  6.25E+5nMAssay Description:Inhibition of human HDAC1 expressed in domain of SMRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed