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Found 30 with Last Name = 'sedig' and Initial = 's'
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333943(CHEMBL1644461 | N1-((2S,3S,5S)-5-((S)-1-(benzylami...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  7nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333944((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  13nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333943(CHEMBL1644461 | N1-((2S,3S,5S)-5-((S)-1-(benzylami...)
Affinity DataKi:  21nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  34nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  56nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333944((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  94nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333948((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  130nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  200nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333947((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  340nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333949((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  450nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333949((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  460nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333948((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  760nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333951((S)-2-{(S)-2-Hydroxy-2-[(S)-19-(methanesulfonyl-me...)
Affinity DataKi:  940nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333947((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333951((S)-2-{(S)-2-Hydroxy-2-[(S)-19-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333943(CHEMBL1644461 | N1-((2S,3S,5S)-5-((S)-1-(benzylami...)
Affinity DataIC50:  30nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333943(CHEMBL1644461 | N1-((2S,3S,5S)-5-((S)-1-(benzylami...)
Affinity DataIC50:  38nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333944((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataIC50:  240nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333949((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333948((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333947((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333951((S)-2-{(S)-2-Hydroxy-2-[(S)-19-(methanesulfonyl-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed