Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 546nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.26E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.93E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition effect on Escherichia coli Wild Type DNA gyrase Supercoiling activityMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.84E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.37E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.59E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.15E+4nMAssay Description:Inhibition of Escherichia coli Quinolone resistant gyrase Supercoiling activityMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.72E+5nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >2.94E+5nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.07E+5nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair