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Found 38 with Last Name = 'seibel' and Initial = 'wl'
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17853(3,5-Pyrazolediamine Inhibitor, 3 | 3-imino-4-[(E)-...)
Affinity DataIC50:  250nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17854(3,5-Pyrazolediamine Inhibitor, 4 | 3-imino-4-[(E)-...)
Affinity DataIC50:  250nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474313(CHEMBL122698)
Affinity DataIC50:  510nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474311(Clinafloxacin)
Affinity DataIC50:  546nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17855(3,5-Pyrazolediamine Inhibitor, 5 | 4-[(E)-2-(3-flu...)
Affinity DataIC50:  550nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17856(3,5-Pyrazolediamine Inhibitor, 6 | 4-[(E)-2-(3-chl...)
Affinity DataIC50:  550nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17857(3,5-Pyrazolediamine Inhibitor, 7 | 4-[(E)-2-(4-flu...)
Affinity DataIC50:  580nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17858(3,5-Pyrazolediamine Inhibitor, 8 | 4-[(E)-2-(4-chl...)
Affinity DataIC50:  1.25E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17859(3,5-Pyrazolediamine Inhibitor, 9 | 3-imino-4-[(E)-...)
Affinity DataIC50:  1.50E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17863(Amino-Alcohol Inhibitor, 12 | methyl 2-[(2S)-2-[(2...)
Affinity DataIC50:  1.70E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17860(3,5-Pyrazolediamine Inhibitor, 2 | 3-[(E)-2-(5-ami...)
Affinity DataIC50:  1.75E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17861(3,5-Pyrazolediamine Inhibitor, 10 | 3-[(E)-2-(5-am...)
Affinity DataIC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474311(Clinafloxacin)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17864(Amino-Alcohol Inhibitor, 13 | methyl (2S)-2-[(2S)-...)
Affinity DataIC50:  3.50E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474312(CHEMBL120948)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474318(CHEMBL123246)
Affinity DataIC50:  4.26E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474310(CHEMBL121176)
Affinity DataIC50:  4.61E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474316(CHEMBL331987)
Affinity DataIC50:  7.93E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474312(CHEMBL120948)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474315(CHEMBL421101)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474309(CHEMBL331076)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition effect on Escherichia coli Wild Type DNA gyrase Supercoiling activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474317(CHEMBL122691)
Affinity DataIC50:  8.84E+3nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17865(Amino-Alcohol Inhibitor, 14 | methyl (2S)-2-[(2S)-...)
Affinity DataIC50:  1.20E+4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474316(CHEMBL331987)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474318(CHEMBL123246)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474319(CHEMBL420897)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17862(({4-[(E)-2-(5-amino-3-imino-3H-pyrazol-4-yl)diazen...)
Affinity DataIC50:  2.00E+4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
The Procter & Gamble Pharmaceuticals

LigandPNGBDBM17866(Amino-Alcohol Inhibitor, 15 | methyl (2S)-2-[(2S)-...)
Affinity DataIC50:  2.50E+4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of a compound toward EcMAP was measured by incubating the compound at various concentrations in the presence of the enzyme an...More data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474313(CHEMBL122698)
Affinity DataIC50:  3.32E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474315(CHEMBL421101)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474317(CHEMBL122691)
Affinity DataIC50:  3.59E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474319(CHEMBL420897)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474314(CHEMBL420884)
Affinity DataIC50:  6.94E+4nMAssay Description:Inhibition of Wild Type DNA gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474309(CHEMBL331076)
Affinity DataIC50:  7.15E+4nMAssay Description:Inhibition of Escherichia coli Quinolone resistant gyrase Supercoiling activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474314(CHEMBL420884)
Affinity DataIC50: >2.72E+5nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50474310(CHEMBL121176)
Affinity DataIC50: >2.94E+5nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  3.07E+5nMAssay Description:Inhibition of Quinolone resistant gyrase Supercoiling Activity in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank