Compile Data Set for Download or QSAR
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Found 13 with Last Name = 'seifert' and Initial = 'jm'
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MYLKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  14nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(CHEMBL1242196 | Dehydromutactin)
Affinity DataKd:  0.0100nMAssay Description:Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectros...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  0.100nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(CHEMBL1242196 | Dehydromutactin)
Affinity DataKd:  0.100nMAssay Description:Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectros...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326011(CHEMBL1240971 | Okicenone)
Affinity DataKd:  85nMAssay Description:Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(CHEMBL1242196 | Dehydromutactin)
Affinity DataKd:  6nMAssay Description:Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  230nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  420nMAssay Description:Binding affinity recombinant HuR RRM1/RRM2 domain by confocal fluctuation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326009(5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...)
Affinity DataKd:  0.100nMAssay Description:Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(CHEMBL1242196 | Dehydromutactin)
Affinity DataKd:  9nMAssay Description:Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectrosc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326011(CHEMBL1240971 | Okicenone)
Affinity DataKd:  90nMAssay Description:Binding affinity to HuR after 24 hrs by microdialysis methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetELAV-like protein 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50326010(CHEMBL1242196 | Dehydromutactin)
Affinity DataKd:  9nMAssay Description:Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectrosc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed