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Found 39 with Last Name = 'seifert' and Initial = 'k'
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86174(CAS_486-12-4 | NSC_5282443 | Triprolidine)
Affinity DataKi:  1.15nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86174(CAS_486-12-4 | NSC_5282443 | Triprolidine)
Affinity DataKi:  3.01nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86171(Arpromidine | CAS_65895 | NSC_65895)
Affinity DataKi:  33.3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86169(BU-E 47)
Affinity DataKi:  53.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86169(BU-E 47)
Affinity DataKi:  255nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86175(Methylhistaprodifen | N-Methyl-2-(3,3-diphenylprop...)
Affinity DataKi:  290nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86170(Dimethylhistaprodifen | N,N-Dimethyl-2-(3,3-diphen...)
Affinity DataKi:  310nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86171(Arpromidine | CAS_65895 | NSC_65895)
Affinity DataKi:  353nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86175(Methylhistaprodifen | N-Methyl-2-(3,3-diphenylprop...)
Affinity DataKi:  370nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86170(Dimethylhistaprodifen | N,N-Dimethyl-2-(3,3-diphen...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86172(2-(3-Chlorophenyl)histamine)
Affinity DataKi:  600nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86173(2-(3-Iodophenyl)histamine)
Affinity DataKi:  610nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM22863(2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...)
Affinity DataKi:  700nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86173(2-(3-Iodophenyl)histamine)
Affinity DataKi:  1.76E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86172(2-(3-Chlorophenyl)histamine)
Affinity DataKi:  1.78E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Affinity DataKi:  2.06E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM22863(2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...)
Affinity DataKi:  2.22E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Affinity DataKi:  4.65E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM22866(2-(1,3-thiazol-2-yl)ethan-1-amine | 2-(2-Thiazolyl...)
Affinity DataKi:  8.49E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300863(CHEMBL568011 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  79.8nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50249489(CHEMBL514344 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  97.9nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300862(CHEMBL577049 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  117nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300861(CHEMBL567378 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  119nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300860(CHEMBL579397 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  163nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300859(CHEMBL568022 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  185nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300858(CHEMBL584688 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  190nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300857(CHEMBL565554 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  224nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300856(CHEMBL583230 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  251nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
UniversitäT Bayreuth

Curated by ChEMBL
LigandPNGBDBM50276581((+/-)-wiedendiol B | CHEMBL456619)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300855(CHEMBL578143 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)
Affinity DataIC50:  876nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300854(CHEMBL583231 | N-(3-(1H-Benzo[d]imidazol-2-yl)phen...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393848(CHEMBL2160032)
Affinity DataEC50:  53.8nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393849(CHEMBL2160031)
Affinity DataEC50:  21.9nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393850(CHEMBL2160030)
Affinity DataEC50:  7.60nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393847(CHEMBL2160033)
Affinity DataEC50:  61.8nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393845(CHEMBL2160035)
Affinity DataEC50:  176nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393851(CHEMBL1221983)
Affinity DataEC50:  8.80nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University Of Leipzig

Curated by ChEMBL
LigandPNGBDBM50393846(CHEMBL2160034)
Affinity DataEC50:  118nMAssay Description:Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression after 48 hrs by renilla luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed