Compile Data Set for Download or QSAR
maximum 50k data
Found 50 with Last Name = 'sekar' and Initial = 'k'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50:  0.692nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50:  0.692nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50088381(ADL 8-2698 | Alvimopan | Entereg)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50088381(ADL 8-2698 | Alvimopan | Entereg)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257769(CHEMBL4100902)
Affinity DataIC50:  18nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257769(CHEMBL4100902)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  45nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257771(CHEMBL4075084)
Affinity DataIC50:  650nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257771(CHEMBL4075084)
Affinity DataIC50:  661nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257774(CHEMBL4104814)
Affinity DataIC50:  780nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257774(CHEMBL4104814)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257767(CHEMBL4097541)
Affinity DataIC50:  800nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257767(CHEMBL4097541)
Affinity DataIC50:  813nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257765(CHEMBL4067441)
Affinity DataIC50:  910nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257765(CHEMBL4067441)
Affinity DataIC50:  948nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257770(CHEMBL4096255)
Affinity DataIC50:  1.26E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257770(CHEMBL4096255)
Affinity DataIC50:  1.29E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257772(CHEMBL4081855)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257772(CHEMBL4081855)
Affinity DataIC50:  1.62E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257768(CHEMBL4084408)
Affinity DataIC50:  1.66E+3nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257768(CHEMBL4084408)
Affinity DataIC50:  1.67E+3nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257766(CHEMBL4105243)
Affinity DataIC50:  1.80E+3nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257764(CHEMBL4061439)
Affinity DataIC50:  1.80E+3nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257766(CHEMBL4105243)
Affinity DataIC50:  1.86E+3nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257764(CHEMBL4061439)
Affinity DataIC50:  1.98E+3nMAssay Description:Agonist activity at recombinant human KOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP level preincubated for 15 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257773(CHEMBL4081523)
Affinity DataIC50:  2.32E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257773(CHEMBL4081523)
Affinity DataIC50:  2.34E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
University Of Madras

Curated by ChEMBL
LigandPNGBDBM50555459(CHEMBL4800560)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of recombinant human topoisomerase 2 assessed as decrease in relaxation of supercoiled pBlue-Script KS(+) plasmid DNA incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
University Of Madras

Curated by ChEMBL
LigandPNGBDBM50555458(CHEMBL4753823)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of recombinant human topoisomerase 2 assessed as decrease in relaxation of supercoiled pBlue-Script KS(+) plasmid DNA incubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539104(CHEMBL4641260)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539103(CHEMBL4636754)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539106(CHEMBL4643799)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539107(CHEMBL4639280)
Affinity DataKd:  700nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539108(CHEMBL4649247)
Affinity DataKd:  300nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539109(CHEMBL4634383)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539110(CHEMBL4634635)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539111(CHEMBL4646109)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539112(CHEMBL4647600)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539113(CHEMBL4649123)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539114(CHEMBL4634892)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539115(CHEMBL4635080)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539116(CHEMBL4648147)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539117(CHEMBL4648396)
Affinity DataKd:  700nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539118(CHEMBL4643228)
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539119(CHEMBL4635630)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539120(CHEMBL4642813)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539121(CHEMBL4646130)
Affinity DataKd:  500nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539102(CHEMBL7075)
Affinity DataKd:  600nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStress-70 protein, mitochondrial(Homo sapiens)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50539105(CHEMBL4636437)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to mortalin substrate binding domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed