TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 stransiently expressed in COS-1 cells using [125I]-PYYMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 stransiently expressed in COS-1 cells using [125I]-PYYMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 stransiently expressed in COS-1 cells using [125I]-PYYMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 stransiently expressed in COS-1 cells using [125I]-PYYMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of 3H-PGD2 from human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 transfected in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at human CRTH2 transfected in human KB8 cells assessed as inhibition of PGD2-induced increase in intracellular Ca2+ by fluo-4AM d...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 4.5nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibitory concentration against radioligand [3H]3-PPP binding to Sigma opioid receptor type 1 in rat brain membraneMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by PDSP Ki Database
Taisho Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 stransiently expressed in COS-1 cells using [125I]-PYYMore data for this Ligand-Target Pair