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Found 17 with Last Name = 'selkoe' and Initial = 'dj'
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  120nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 40) production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  120nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 40 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  130nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated amyloid beta (1 to 42) production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  130nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50:  360nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 40 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50:  400nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 42 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163320(CHEMBL3792858)
Affinity DataIC50:  580nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 40 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50:  620nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50164884(CHEMBL3799833)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as inhibition of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163314(CHEMBL3793083)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50164883(CHEMBL3800321)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as inhibition of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50500995(CHEMBL3799376)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163311(CHEMBL3793752)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163312(CHEMBL3792849)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50163309(CHEMBL3794005)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50500994(CHEMBL3798465)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gamma secretase (unknown origin)-mediated notch processing by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163310(CHEMBL3793199)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed