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Found 387 with Last Name = 'selvam' and Initial = 'c'
TargetAcetylcholinesterase(Rattus norvegicus (rat))TBA
LigandPNGBDBM50100576(CHEMBL3321885)
Affinity DataIC50:  97nMAssay Description:Antagonism of the norepinephrine induced contraction of rat isolated prostatic vas deferens.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 2 from sheep placenta at 100 uMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  2.26E+3nMAssay Description:In vitro inhibitory concentration of the compound against ram seminal vescicle prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50615216(CHEMBL5290636)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human Alpha-glucosidaseMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM23451(5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50163748((E)-3,5-Bis[beta-(4-Hydroxy-3-methoxyphenyl)-ethen...)
Affinity DataIC50:  9.70E+3nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50163745(4,40-(1E,10E)-2,20-(Isoxazole-3,5-diyl)bis(ethene-...)
Affinity DataIC50:  1.07E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  1.11E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50359629(TROLOX)
Affinity DataIC50:  1.31E+4nMAssay Description:Anti-oxidant activity in DPPH radical scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 1 of ram seminal vesicles at 100 uMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50163747(4-((E)-2-{5-[(E)-2-(4-Hydroxy-phenyl)-vinyl]-1H-py...)
Affinity DataIC50:  1.55E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50163743(4-((E)-2-{5-[(E)-2-(4-Hydroxy-phenyl)-vinyl]-isoxa...)
Affinity DataIC50:  1.90E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50163744((1E,4Z,6E)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl...)
Affinity DataIC50:  2.14E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50615215(CHEMBL5290615)
Affinity DataIC50:  3.05E+4nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50163746(4-((E)-2-{3-[(E)-2-(4-hydroxyphenyl)vinyl]-1H-pyra...)
Affinity DataIC50:  3.24E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50059989((1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-phenyl)-he...)
Affinity DataIC50:  3.64E+4nMAssay Description:Anti-oxidant activity in DPPH radicak scavenging assay; n=3-4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)TBA
LigandPNGBDBM23451(5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of Influenza A virus H5N1 neuraminidaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50452027(CHEMBL2096754)
Affinity DataIC50:  4.52E+4nMAssay Description:In vitro inhibitory concentration of the compound against ram seminal vescicle prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50615213(CHEMBL5279690)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibition of Alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50615214(CHEMBL5269655)
Affinity DataIC50:  1.74E+5nMAssay Description:Inhibition of Alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50452027(CHEMBL2096754)
Affinity DataIC50:  1.80E+5nMAssay Description:In vitro inhibitory concentration of the compound against sheep placenta Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  2.66E+5nMAssay Description:Inhibitory concentration against Prostaglandin G/H synthase 2 from sheep placenta at 100 uMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  2.66E+5nMAssay Description:In vitro inhibitory concentration of the compound against sheep placenta Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  1.10E+6nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as increase in intracellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(RAT)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50446782(CHEMBL3114672)
Affinity DataIC50:  2.30E+6nMAssay Description:Antagonist activity at rat GluN1a/mouse GluN2B receptors expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glucine induced cu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  2.08E+3nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50174527((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50174527((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220009(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Affinity DataEC50:  1.72E+3nMAssay Description:Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50174527((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Affinity DataEC50:  1.10E+6nMAssay Description:Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220011(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Affinity DataEC50:  1.97E+5nMAssay Description:Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220009(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Affinity DataEC50:  2.78E+4nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  4.40E+5nMAssay Description:Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220009(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220011(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  128nMAssay Description:Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220011(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Affinity DataEC50:  730nMAssay Description:Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50174527((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...)
Affinity DataEC50:  4.12E+5nMAssay Description:Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220011(CHEMBL243925 | L-(+)-2-amino-4-thiophosphonobutyri...)
Affinity DataEC50:  54nMAssay Description:Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50220009(CHEMBL241972 | L-(+)-2-amino-4-[(hydroxy)phosphiny...)
Affinity DataEC50:  4.05E+3nMAssay Description:Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314793((S)-3-amino-3-carboxypropyl-2'-carboxyethyl phosph...)
Affinity DataEC50:  5.20E+4nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314794((3S)-2-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  5.70E+4nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314796((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50:  4.90E+4nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Universite Paris Descartes

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells assessed as increase in intracellular calcium level after 1 hr by fluorescence micro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50314797((3S)-3-[((3-Amino-3-carboxy)propyl)(hydroxy)phosph...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  3.06E+5nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50060137((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...)
Affinity DataEC50:  2.80E+5nMAssay Description:Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
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