Found 482 with Last Name = 'sengupta' and Initial = 's' TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: <0.510nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of human ALK6 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human FLT4 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide as substrate in presence of [gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human ALK3 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM ATP by radiometric kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea University
Curated by ChEMBL
Korea University
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
