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Found 100 with Last Name = 'seraj' and Initial = 'j'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50:  7nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206281(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  7nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206272(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  15nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206279(5-chloro-4-(1H-indol-6-yl)-N-(4-(2-(pyrrolidin-1-y...)
Affinity DataIC50:  16nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206285(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  19nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212033(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(4-methyl...)
Affinity DataIC50:  21nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206271(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  26nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212029(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-morpholin...)
Affinity DataIC50:  27nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  33nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50:  37nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206281(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  48nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212040(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-hydroxyet...)
Affinity DataIC50:  52nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212034(4-(4-(2-aminopropan-2-yl)phenyl)-2-(3-(2-morpholin...)
Affinity DataIC50:  55nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212043(4-phenyl-2-(4-(pyrrolidin-1-ylmethyl)phenylamino)p...)
Affinity DataIC50:  61nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50:  69nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206278(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  76nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212021(2-(4-(2-hydroxyethyl)phenylamino)-4-(thiophen-2-yl...)
Affinity DataIC50:  82nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212017(2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-5-yl...)
Affinity DataIC50:  90nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212036(2-(3-methoxy-4-(pyrrolidin-1-ylmethyl)phenylamino)...)
Affinity DataIC50:  91nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212014(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-(2-ethyl-...)
Affinity DataIC50:  94nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206284(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  103nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212030(4-phenyl-2-(4-(2-(pyrrolidin-1-yl)ethyl)phenylamin...)
Affinity DataIC50:  110nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206280(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50:  148nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212016(2-(4-(2-hydroxyethyl)phenylamino)-4-(4-methoxyphen...)
Affinity DataIC50:  150nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50:  159nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206282(5-chloro-4-(1H-indol-3-yl)-N-(4-(2-(4-methylpipera...)
Affinity DataIC50:  180nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212027(4-(4-bromophenyl)-2-(4-(2-hydroxyethyl)phenylamino...)
Affinity DataIC50:  180nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212031(2-(4-(3-morpholino-3-oxopropyl)phenylamino)-4-phen...)
Affinity DataIC50:  180nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212022(4-(5-cyano-2-(4-(2-hydroxyethyl)phenylamino)pyrimi...)
Affinity DataIC50:  200nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212028(2-(4-(2-hydroxyethyl)phenylamino)-4-phenylpyrimidi...)
Affinity DataIC50:  200nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206273(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  216nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206274(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  314nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206270(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  334nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212026(4-(benzo[d]thiazol-2-yl)-2-(4-(2-hydroxyethyl)phen...)
Affinity DataIC50:  340nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206269(4-(4-(2-aminopropan-2-yl)phenyl)-N-(3-bromophenyl)...)
Affinity DataIC50:  348nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212038(2-(3-(morpholinomethyl)phenylamino)-4-phenylpyrimi...)
Affinity DataIC50:  360nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212019(2-(3-methoxyphenylamino)-4-phenylpyrimidine-5-carb...)
Affinity DataIC50:  380nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212013(2-(4-(2-hydroxyethyl)phenylamino)-4-(4-(2-hydroxyp...)
Affinity DataIC50:  410nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212032(2-(2-methyl-1H-indol-5-ylamino)-4-phenylpyrimidine...)
Affinity DataIC50:  410nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212017(2-(4-(2-hydroxyethyl)phenylamino)-4-(1H-indol-5-yl...)
Affinity DataIC50:  410nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50:  439nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212039(4-(4-(2-aminopropan-2-yl)phenyl)-2-(4-(2-morpholin...)
Affinity DataIC50:  450nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206270(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  455nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206275(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(t...)
Affinity DataIC50:  461nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212021(2-(4-(2-hydroxyethyl)phenylamino)-4-(thiophen-2-yl...)
Affinity DataIC50:  470nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212035(2-(4-methoxyphenylamino)-4-phenylpyrimidine-5-carb...)
Affinity DataIC50:  490nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206273(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  540nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50212026(4-(benzo[d]thiazol-2-yl)-2-(4-(2-hydroxyethyl)phen...)
Affinity DataIC50:  560nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50:  687nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206274(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...)
Affinity DataIC50:  781nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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