Found 31 with Last Name = 'serin' and Initial = 'g' TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 12.3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 12.4nMAssay Description:Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 36.1nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 48.1nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 63.3nMAssay Description:Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in p...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate assessed as reduction in substrate hydroxylation incubated for 30 mins i...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate assessed as reduction in substrate hydroxylation incubated for 30 mins i...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate assessed as reduction in substrate hydroxylation incubated for 30 mins...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate assessed as reduction in substrate hydroxylation incubated for 30 mins in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate assessed as reduction in substrate hydroxylation incubated for 5 m...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate assessed as reduction in substrate hydroxylation incubated for 30 mins in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins in ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate assessed as reduction in substrate hydroxylation incubated for 30 min...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate assessed as reduction in substrate hydroxylation incubated for 5 mins...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using as phenacetin substrate assessed as reduction in O-deethylation of phenacetin incubated for 5 mi...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 6.37E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate assessed as reduction in substrate hydroxylation incubated for 30 mins in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate assessed as reduction in substrate hydroxylation incubated for 30 ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using as phenacetin substrate assessed as reduction in O-deethylation of phenacetin incubated for 30 m...More data for this Ligand-Target Pair
Ligand Info
