Affinity DataKi: 0.850nMAssay Description:Binding affinity to bovine brain membrane BzR assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to bovine brain membrane BzR assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibition of human Cathepsin K assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-PK11195 from rat kidney mitochondrial membrane TSPO receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]-PK11195 from rat kidney mitochondrial membrane TSPO receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]-PK11195 from rat kidney mitochondrial membrane TSPO receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Displacement of [3H]-PK11195 from rat kidney mitochondrial membrane TSPO receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 11.8nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 17.4nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of Calpain I (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 20.2nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity rat kidney mitochondrial membrane TSPO receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 27.2nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of human Cathepsin B assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of Calpain I (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]-flumazenil specific binding at rat GABA-A alpha1-beta2-gamma2 receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of human Calpain I assessed as dissociation constant using Suc-Leu-Tyr-AMC as substrate preincubated for 15 mins followed by compound addi...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 108nMAssay Description:Displacement of [3H] PK11195 from TSPO in human U-87 MGcell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Binding affinity to bovine brain membrane BzR assessed as inhibition constantMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 137nMAssay Description:Inhibition of human Cathepsin L assessed as inhibition constantMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 137nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 202nMAssay Description:Displacement of [3H] PK11195 from TSPO (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 202nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 224nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 231nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
Affinity DataKi: 231nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
Università
Curated by ChEMBL
Affinity DataKi: 239nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha5-beta3-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Università
Curated by ChEMBL
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Curated by ChEMBL
Affinity DataKi: 283nMAssay Description:Inhibition of [3H]-flumazenil binding to rat alpha3-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 332nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Displacement of [125I]-AB-MECA from Adenosine A3 receptor in bovine cortical membranes in the presence of 20 nM DPCPX.More data for this Ligand-Target Pair
Affinity DataKi: 438nMAssay Description:Displacement of [3H] PK11195 from TSPO (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 511nMAssay Description:Displacement of [3H]-CHA from Adenosine A1 receptor in bovine cortical membranes.More data for this Ligand-Target Pair