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Found 17 with Last Name = 'severin' and Initial = 'jm'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81731(HSP90 Inhibitor, 5)
Affinity DataKi:  60nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81730(HSP90 Inhibitor, 4)
Affinity DataKi:  170nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81729(HSP90 Inhibitor, 1 | hsp90_125)
Affinity DataKi:  320nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81732(HSP90 Inhibitor, 6)
Affinity DataKi:  1.90E+3nM ΔG°:  -32.7kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81733(HSP90 Inhibitor, 7)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50270588(4-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE | CH...)
Affinity DataKi:  1.80E+4nM ΔG°:  -27.1kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14486((2R,3R,4S,5R)-2-(2-amino-9-iodo-3,5,7-triazabicycl...)
Affinity DataIC50:  0.900nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14494(6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethynyl}-5-(3...)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14491(5-(2H-1,3-benzodioxol-5-yl)-6-{2-[4-(dimethylamino...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14489(6-{2-[4-(dimethylamino)phenyl]ethynyl}-5-phenylpyr...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14493(5-benzyl-6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethy...)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14488(5-[4-(dimethylamino)phenyl]-6-{2-[6-(morpholin-4-y...)
Affinity DataIC50:  68nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14492(6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethynyl}pyrim...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM14490(6-{2-[4-(dimethylamino)phenyl]ethynyl}-2-methyl-5-...)
Affinity DataIC50: >1.00E+3nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50270588(4-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE | CH...)
Affinity DataKd:  2.00E+4nMpH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using NMR fragment-based screening assay.More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81729(HSP90 Inhibitor, 1 | hsp90_125)
Affinity DataKd: <1.00E+4nMpH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using NMR fragment-based screening assay.More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50270609((3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H...)
Affinity DataKd:  1.50E+5nMpH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using NMR fragment-based screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed