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Found 74 with Last Name = 'shah' and Initial = 'jr'
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35928(3-(9,10-dihydroanthracen-9-yl)-N,N-dimethylpropan-...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35927(3-(9,10-dihydroanthracen-9-yl)-N-methylpropan-1-am...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35925(9,10-dihydroanthracene(DHA), 2c)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35927(3-(9,10-dihydroanthracen-9-yl)-N-methylpropan-1-am...)
Affinity DataKi:  13nM ΔG°:  -44.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35920(9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...)
Affinity DataKi:  20nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310096((7,12-dihydro-3-methoxytetraphen-12-yl)methanamine...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]Ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35928(3-(9,10-dihydroanthracen-9-yl)-N,N-dimethylpropan-...)
Affinity DataKi:  22nM ΔG°:  -43.4kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35922((9,10-Dihydro-anthracen-9-ylmethyl)-dimethyl-amine...)
Affinity DataKi:  25nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35926(3-(9,10-Dihydro-anthracen-9-yl)-propylamine | 9,10...)
Affinity DataKi:  32nM ΔG°:  -42.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35924(9,10-dihydroanthracene(DHA), 2b)
Affinity DataKi:  48nM ΔG°:  -41.8kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35921((9,10-Dihydro-anthracen-9-ylmethyl)-methyl-amine |...)
Affinity DataKi:  52nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35933(diphenylalkylamine (DPA), 5b)
Affinity DataKi:  64nM ΔG°:  -41.1kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35937(diphenylalkylamine (DPA), 6c)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35934(diphenylalkylamine (DPA), 5c)
Affinity DataKi:  75nM ΔG°:  -40.7kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35925(9,10-dihydroanthracene(DHA), 2c)
Affinity DataKi:  84nM ΔG°:  -40.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35924(9,10-dihydroanthracene(DHA), 2b)
Affinity DataKi:  92nM ΔG°:  -39.9kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35923(2-(9,10-Dihydro-anthracen-9-yl)-ethylamine | 9,10-...)
Affinity DataKi:  137nM ΔG°:  -39.2kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35926(3-(9,10-Dihydro-anthracen-9-yl)-propylamine | 9,10...)
Affinity DataKi:  175nM ΔG°:  -38.6kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35921((9,10-Dihydro-anthracen-9-ylmethyl)-methyl-amine |...)
Affinity DataKi:  189nM ΔG°:  -38.4kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35920(9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...)
Affinity DataKi:  197nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310098(CHEMBL609328 | N-((9,10-Dihydroanthracen-9-yl)meth...)
Affinity DataKi:  223nMAssay Description:Displacement of [3H]Ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310097(CHEMBL590241 | N-((9,10-Dihydroanthracen-9-yl)meth...)
Affinity DataKi:  242nMAssay Description:Displacement of [3H]Pyrilamine from human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310099(CHEMBL597528 | N-((9,10-Dihydroanthracen-9-yl)meth...)
Affinity DataKi:  365nMAssay Description:Displacement of [3H]Ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35936(diphenylalkylamine (DPA), 6b)
Affinity DataKi:  386nM ΔG°:  -36.6kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310097(CHEMBL590241 | N-((9,10-Dihydroanthracen-9-yl)meth...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]Ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35923(2-(9,10-Dihydro-anthracen-9-yl)-ethylamine | 9,10-...)
Affinity DataKi:  480nM ΔG°:  -35.8kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35922((9,10-Dihydro-anthracen-9-ylmethyl)-dimethyl-amine...)
Affinity DataKi:  540nM ΔG°:  -35.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50097644(9-(N-benzylaminomethyl)-9,10-dihydroanthracene | B...)
Affinity DataKi:  721nMAssay Description:Displacement of [3H]Ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310098(CHEMBL609328 | N-((9,10-Dihydroanthracen-9-yl)meth...)
Affinity DataKi:  725nMAssay Description:Displacement of [3H]Pyrilamine from human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35936(diphenylalkylamine (DPA), 6b)
Affinity DataKi:  754nM ΔG°:  -34.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310099(CHEMBL597528 | N-((9,10-Dihydroanthracen-9-yl)meth...)
Affinity DataKi:  964nMAssay Description:Displacement of [3H]Pyrilamine from human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35937(diphenylalkylamine (DPA), 6c)
Affinity DataKi:  1.15E+3nM ΔG°:  -33.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35933(diphenylalkylamine (DPA), 5b)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.0kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35934(diphenylalkylamine (DPA), 5c)
Affinity DataKi:  1.64E+3nM ΔG°:  -32.8kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35935(diphenylalkylamine (DPA), 6a)
Affinity DataKi:  1.67E+3nM ΔG°:  -33.0kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35935(diphenylalkylamine (DPA), 6a)
Affinity DataKi:  2.59E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM50310096((7,12-dihydro-3-methoxytetraphen-12-yl)methanamine...)
Affinity DataKi:  2.64E+3nMAssay Description:Displacement of [3H]Pyrilamine from human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35932(diphenylalkylamine (DPA), 5a)
Affinity DataKi:  2.76E+3nM ΔG°:  -31.7kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)
Affinity DataKi:  4.61E+3nM ΔG°:  -30.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35931(2,2-diphenylethyl(dimethyl)amine;hydrochloride | d...)
Affinity DataKi:  5.17E+3nM ΔG°:  -30.2kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35931(2,2-diphenylethyl(dimethyl)amine;hydrochloride | d...)
Affinity DataKi:  7.36E+3nM ΔG°:  -29.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35930(diphenylalkylamine (DPA), 4b)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35932(diphenylalkylamine (DPA), 5a)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35930(diphenylalkylamine (DPA), 4b)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

LigandPNGBDBM35929(2,2-Diphenyl-ethylamine | 2,2-diphenylethanamine |...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50365156(CHEMBL1949866)
Affinity DataIC50:  400nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50068761(2,8-Dimethyl-3H-quinazolin-4-one | CHEMBL151549)
Affinity DataIC50:  490nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50365150(CHEMBL1949858)
Affinity DataIC50:  760nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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