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Found 292 with Last Name = 'shamim' and Initial = 'mt'
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50007838(8-Cyclohexyl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50007838(8-Cyclohexyl-1,3-dipropyl-3,7-dihydro-purine-2,6-d...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82013(8-(2-Amino-4-chloro-phenyl)-1,3-dipropyl-3,7-dihyd...)
Affinity DataKi:  2.5nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82010(1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine | 8-(4-Hy...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82010(1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine | 8-(4-Hy...)
Affinity DataKi:  2.90nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021004(8-(2,4-Diamino-phenyl)-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82025(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Affinity DataKi:  5.90nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021453(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  7nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021453(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  7nMAssay Description:Binding affinity against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021456(Acetic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetr...)
Affinity DataKi:  8nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021452(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82025(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Affinity DataKi:  10nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82025(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Affinity DataKi:  10nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021448(8-(2-Hydroxy-4-methoxy-phenyl)-1,3-dipropyl-3,7-di...)
Affinity DataKi:  11nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021456(Acetic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetr...)
Affinity DataKi:  12nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021004(8-(2,4-Diamino-phenyl)-1,3-dipropyl-3,7-dihydro-pu...)
Affinity DataKi:  13nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82025(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Affinity DataKi:  13nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82025(1,3-Dipropyl-8-phenylxanthine | 8-Phenyl-1,3-dipro...)
Affinity DataKi:  13nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021455(8-(4-Methoxy-phenyl)-1,3-dipropyl-3,7-dihydro-puri...)
Affinity DataKi:  14nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021449(8-(2,4-Dihydroxy-phenyl)-1,3-dipropyl-3,7-dihydro-...)
Affinity DataKi:  15nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50018152(8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione | C...)
Affinity DataKi:  20nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM81925(8-Cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-...)
Affinity DataKi:  24nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021450(8-(4-Amino-phenyl)-1,3-dipropyl-3,7-dihydro-purine...)
Affinity DataKi:  27nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021450(8-(4-Amino-phenyl)-1,3-dipropyl-3,7-dihydro-purine...)
Affinity DataKi:  28nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021457(8-(2,3-Dihydroxy-phenyl)-1,3-dipropyl-3,7-dihydro-...)
Affinity DataKi:  33nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50018152(8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione | C...)
Affinity DataKi:  36nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021460(8-(3-Chloro-4-hydroxy-phenyl)-1,3-dipropyl-3,7-dih...)
Affinity DataKi:  36nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50014528(8-Cyclohexyl-1,1,3-trimethyl-3,9-dihydro-purine-2,...)
Affinity DataKi:  41nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021458(8-(4-Dimethylamino-phenyl)-1,3-dipropyl-3,7-dihydr...)
Affinity DataKi:  45nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50227340(CHEMBL27155)
Affinity DataKi:  48nMAssay Description:Inhibition of 5'-(N-ethylcarbamoyl)adenosine-elicited stimulation of adenylate cyclase in human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine | 8-(4-Hy...)
Affinity DataKi:  50nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM82010(1,3-Dipropyl-8-(4-hydroxyphenyl)xanthine | 8-(4-Hy...)
Affinity DataKi:  50nMAssay Description:Antagonism of cyclic [3H]AMP accumulation in guinea pig cerebral cortical slices (elicited by 15 uM 2-chloroadenosine at adenosine A2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM82012(8-(4-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-puri...)
Affinity DataKi:  50nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021451(8-(2,4-Difluoro-phenyl)-1,3-dipropyl-3,7-dihydro-p...)
Affinity DataKi:  51nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50021453(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  54nMAssay Description:Inhibition of 5'-(N-ethylcarbamoyl)adenosine-elicited stimulation of adenylate cyclase in human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50018152(8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione | C...)
Affinity DataKi:  67nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021453(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  72nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021453(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  72nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50018152(8-Phenyl-1-propyl-3,7-dihydro-purine-2,6-dione | C...)
Affinity DataKi:  73nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via Adenosine A2 receptor in rat PC12 membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50227341(CHEMBL347866)
Affinity DataKi:  77nMAssay Description:Inhibition of 5'-(N-ethylcarbamoyl)adenosine-elicited stimulation of adenylate cyclase in human platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50018168(8-Cyclohexyl-7-methyl-1,3-dipropyl-3,7-dihydro-pur...)
Affinity DataKi:  85nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021455(8-(4-Methoxy-phenyl)-1,3-dipropyl-3,7-dihydro-puri...)
Affinity DataKi:  95nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021458(8-(4-Dimethylamino-phenyl)-1,3-dipropyl-3,7-dihydr...)
Affinity DataKi:  100nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50018151(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  110nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50014528(8-Cyclohexyl-1,1,3-trimethyl-3,9-dihydro-purine-2,...)
Affinity DataKi:  110nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50018151(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  110nMAssay Description:Antagonism of cyclic [3H]AMP accumulation in guinea pig cerebral cortical slices (elicited by 15 uM 2-chloroadenosine at adenosine A2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021452(4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...)
Affinity DataKi:  115nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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