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Found 834 with Last Name = 'shang' and Initial = 'j'
TargetCoagulation factor IX(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125977(CHEMBL3627897)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human factor 9a using CH3SO2-DCHG-Gly-Arg-AFC.AcOH as substrate preinubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50151405(CHEMBL3775211 | US10189819, Example 79)
Affinity DataKi:  11nMAssay Description:Inhibition of human factor 9a using CH3SO2-DCHG-Gly-Arg-AFC.AcOH as substrate preinubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50204495(CHEMBL3921061)
Affinity DataKi:  160nMAssay Description:Non-competitive inhibition of human serum BChE using S-Butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486243(MONOSULFURON ESTER)
Affinity DataKi:  260nMAssay Description:Inhibition of wild type Arabidopsis thaliana acetohydroxyacid synthase colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)
Affinity DataKi:  420nMAssay Description:Displacement of fluormone PanPPAR green tracer ligand from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50103521(Actos | CHEBI:8228 | Duetact | Pioglitazone | US10...)
Affinity DataKi:  420nMAssay Description:Displacement of fluormone PanPPAR green tracer ligand from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology

Curated by ChEMBL
LigandPNGBDBM50204495(CHEMBL3921061)
Affinity DataKi:  520nMAssay Description:Non-competitive inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50530214(CHEBI:82937 | Leriglitazone | Min-102)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of fluormone PanPPAR green tracer ligand from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50530214(CHEBI:82937 | Leriglitazone | Min-102)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of fluormone PanPPAR green tracer ligand from human 6His-tagged PPARgamma isoform 1 LBD (203 to 477 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486242(CHEMBL2230130)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of wild type Arabidopsis thaliana acetohydroxyacid synthase colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125977(CHEMBL3627897)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of human factor 10a using n-Acetyl-KPR-AFC as substrate preinubated for 30 mins followed by substrate addition measured after 1 hr by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486241(CHEBI:5869 | IMAZAQUIN)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of wild type Arabidopsis thaliana acetohydroxyacid synthase colorimetric assayMore data for this Ligand-Target Pair
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486245(CHEMBL2230131)
Affinity DataKi:  4.69E+3nMAssay Description:Inhibition of wild type Arabidopsis thaliana acetohydroxyacid synthase colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486244(CHEMBL2229985)
Affinity DataKi:  5.57E+3nMAssay Description:Inhibition of wild type Arabidopsis thaliana acetohydroxyacid synthase colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486243(MONOSULFURON ESTER)
Affinity DataKi:  8.53E+3nMAssay Description:Inhibition of Arabidopsis thaliana acetohydroxyacid synthase W574L mutant colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486242(CHEMBL2230130)
Affinity DataKi:  2.45E+4nMAssay Description:Inhibition of Arabidopsis thaliana acetohydroxyacid synthase W574L mutant colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486245(CHEMBL2230131)
Affinity DataKi:  2.57E+4nMAssay Description:Inhibition of Arabidopsis thaliana acetohydroxyacid synthase W574L mutant colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486244(CHEMBL2229985)
Affinity DataKi:  2.71E+4nMAssay Description:Inhibition of Arabidopsis thaliana acetohydroxyacid synthase W574L mutant colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetolactate synthase, chloroplastic(Arabidopsis thaliana)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50486241(CHEBI:5869 | IMAZAQUIN)
Affinity DataKi:  4.70E+5nMAssay Description:Inhibition of Arabidopsis thaliana acetohydroxyacid synthase W574L mutant colorimetric assayMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468144(CHEMBL4286244)
Affinity DataIC50:  0.100nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468160(CHEMBL4293458)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468136(CHEMBL4287248)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50374938(CHEMBL402163)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of human recombinant DPP4 expressed in insect cellMore data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468144(CHEMBL4286244)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM123216(US8742110, 3-1)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468136(CHEMBL4287248)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468146(CHEMBL4285917)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468157(CHEMBL4289661)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468157(CHEMBL4289661)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468160(CHEMBL4293458)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468129(CHEMBL4288848)
Affinity DataIC50:  0.600nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468153(CHEMBL4279392)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468133(CHEMBL4278161)
Affinity DataIC50:  0.700nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468159(CHEMBL4278328)
Affinity DataIC50:  0.700nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468146(CHEMBL4285917)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM123216(US8742110, 3-1)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468133(CHEMBL4278161)
Affinity DataIC50:  0.800nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468150(CHEMBL4277006)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468159(CHEMBL4278328)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468139(CHEMBL4288391)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50322981(CHEMBL1210207 | N-(1-((2,6-diethoxy-4'-fluorobiphe...)
Affinity DataIC50:  1nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468145(CHEMBL4278915)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50468160(CHEMBL4293458)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM123274(US8742110, 5-10)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468139(CHEMBL4288391)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468143(CHEMBL4281446)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50468128(CHEMBL4282052)
Affinity DataIC50:  1.20nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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