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Found 245 with Last Name = 'sheen' and Initial = 'jt'
LigandPNGBDBM194105(US9200001, 19)
Affinity DataKi:  0.00200nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194104(US9200001, 18)
Affinity DataKi:  0.00200nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194113(US9200001, 28)
Affinity DataKi:  0.00300nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194090(US9200001, 3)
Affinity DataKi:  0.00400nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194122(US9200001, 38)
Affinity DataKi:  0.00500nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194223(US9200001, 26)
Affinity DataKi:  0.00500nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194099(US9200001, 13)
Affinity DataKi:  0.0100nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194089(US9200001, 2)
Affinity DataKi:  0.0230nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194111(US9200001, 25)
Affinity DataKi:  0.0270nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194102(US9200001, 16)
Affinity DataKi:  0.0270nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194095(US9200001, 8)
Affinity DataKi:  0.0280nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194101(US9200001, 15)
Affinity DataKi:  0.0560nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM236019(US9365562, 57)
Affinity DataKi:  0.0650nM ΔG°:  -58.1kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM194119(US9200001, 34)
Affinity DataKi:  0.0680nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194094(US9200001, 7)
Affinity DataKi:  0.0730nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194145(US9200001, 61)
Affinity DataKi:  0.0850nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194106(US9200001, 20)
Affinity DataKi:  0.110nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM236020(US9365562, 58)
Affinity DataKi:  0.120nM ΔG°:  -56.6kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236035(US9365562, 73)
Affinity DataKi:  0.130nM ΔG°:  -56.4kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
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LigandPNGBDBM194134(US9200001, 50)
Affinity DataKi:  0.140nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194092(US9200001, 5)
Affinity DataKi:  0.140nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM235985(US9365562, 23)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM194133(US9200001, 49)
Affinity DataKi:  0.210nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194120(US9200001, 35)
Affinity DataKi:  0.210nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM236018(US9365562, 56)
Affinity DataKi:  0.240nM ΔG°:  -54.9kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
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LigandPNGBDBM236039(US9365562, 77)
Affinity DataKi:  0.260nM ΔG°:  -54.7kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236010(US9365562, 48)
Affinity DataKi:  0.260nM ΔG°:  -54.7kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236034(US9365562, 72)
Affinity DataKi:  0.280nM ΔG°:  -54.5kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236029(US9365562, 67)
Affinity DataKi:  0.280nM ΔG°:  -54.5kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236041(US9365562, 79)
Affinity DataKi:  0.280nM ΔG°:  -54.5kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236040(US9365562, 78)
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236012(US9365562, 50)
Affinity DataKi:  0.350nM ΔG°:  -54.0kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
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LigandPNGBDBM194153(US9200001, 69)
Affinity DataKi:  0.370nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194217(US9200001, 133)
Affinity DataKi:  0.370nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM236032(US9365562, 70)
Affinity DataKi:  0.380nM ΔG°:  -53.8kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
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LigandPNGBDBM194127(US9200001, 43)
Affinity DataKi:  0.390nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM194176(US9200001, 92)
Affinity DataKi:  0.400nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM236026(US9365562, 64)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236033(US9365562, 71)
Affinity DataKi:  0.400nM ΔG°:  -53.6kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236000(US9365562, 38)
Affinity DataKi:  0.410nM ΔG°:  -53.6kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM194220(US9200001, 136)
Affinity DataKi:  0.420nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM236023(US9365562, 61)
Affinity DataKi:  0.460nM ΔG°:  -53.3kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236005(US9365562, 43)
Affinity DataKi:  0.490nM ΔG°:  -53.1kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM236036(US9365562, 74)
Affinity DataKi:  0.490nM ΔG°:  -53.1kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM194175(US9200001, 91)
Affinity DataKi:  0.490nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM194126(US9200001, 42)
Affinity DataKi:  0.5nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM235968(US9365562, 6)
Affinity DataKi:  0.530nM ΔG°:  -52.9kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM194147(US9200001, 63)
Affinity DataKi:  0.540nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
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LigandPNGBDBM235995(US9365562, 33)
Affinity DataKi:  0.540nM ΔG°:  -52.9kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM194218(US9200001, 134)
Affinity DataKi:  0.580nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exp...More data for this Ligand-Target Pair
In DepthDetails US Patent
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